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Key Documents

Safety Information

T3902

Sigma-Aldrich

Thiamine hydrochloride

suitable for plant cell culture, BioReagent

Synonym(s):

Aneurine hydrochloride, Vitamin B1 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H17ClN4OS · HCl
CAS Number:
Molecular Weight:
337.27
Beilstein:
3851771
EC Number:
MDL number:
UNSPSC Code:
12352200
eCl@ss:
34058006
PubChem Substance ID:

product line

BioReagent

technique(s)

cell culture | plant: suitable

mp

250 °C (dec.) (lit.)

application(s)

agriculture

SMILES string

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

InChI key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

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Biochem/physiol Actions

Thiamine is a precursor of thiamine diphosphate, a coenzyme for enzymes that catalyse two-carbon unit transfer reactions by enzymes such as pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase; branched-chain α-keto acid dehydrogenase; 2-hydroxyphytanoyl-CoA lyase and transketolase. Thiamine is added to a variety of plant cell cultures to enhance processes such as shoot formation.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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A Baruah et al.
Indian journal of experimental biology, 39(9), 947-949 (2002-02-08)
A protocol was developed for high frequency plant regeneration in H. patulum by shoot-tip culture. H. patulum plants were collected from a wild source growing at high altitude in the eastern Himalayas. Multiple buds were initiated from shoot-tips cultured on
M Ramesh et al.
Indian journal of experimental biology, 47(1), 68-74 (2009-03-26)
A reliable and reproducible protocol has been developed for high frequency plant regeneration from 4-5 mm long leaf base segments of 4 days old in vitro germinated seedlings of indica rice (Oryza sativa) cultivar Rasi. The effect of age of
Joseph E Kerschner et al.
Archives of otolaryngology--head & neck surgery, 135(1), 33-39 (2009-01-21)
To investigate genetic differences in middle ear mucosa (MEM) with nontypeable Haemophilus influenzae (NTHi) infection. Genetic upregulation and downregulation occurs in MEM during otitis media (OM) pathogenesis. A comprehensive assessment of these genetic differences using the techniques of complementary DNA
Samir Ahmed El-Shazly et al.
International journal of immunopathology and pharmacology, 28(2), 227-239 (2015-03-31)
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia due to abnormalities in either insulin secretion or action. A range of vanadium complexes have been synthesized and demonstrated to be effective in lowering hyperglycemia. Thiamine administration was also
Ashish K Singh et al.
Alcoholism, clinical and experimental research, 38(7), 2127-2137 (2014-06-17)
Chronic ethanol (EtOH) consumption is associated with oxidative tissue damage, decrease in antioxidant enzyme activities, and increase in hepatic and plasma lipids. This study investigates the effect of modified probiotic Escherichia coli Nissle 1917 (EcN) secreting pyrroloquinoline quinone (PQQ) against

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