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Merck
CN

T3568

TrypZean® bovine

recombinant, expressed in corn, lyophilized powder, ≥3,350 units/mg solid (USP)

Synonym(s):

Trypsin bovine

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About This Item

CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-650-8
MDL number:
EC Number:
Specific activity:
≥3,350 units/mg solid (USP)
Recombinant:
expressed in corn
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recombinant

expressed in corn

Quality Level

form

lyophilized powder

specific activity

≥3,350 units/mg solid (USP)

UniProt accession no.

storage temp.

−20°C

Gene Information

cow ... TRYP8(282603)

General description

TrypZean® eliminates the introduction of animal source contaminants found in traditional bovine and porcine trypsins.

Application

Eliminates the introduction of animal source contaminants found in traditional bovine and porcine trypsins.
TrypZean® has been used in a study to assess the use of animal protein-free products for passaging adherent human adipose-derived stromal/stem cells. TrypZean® has also been used in a study to compare a recombinant trypsin with the porcine pancreatic extract on sperm used for the in vitro production of bovine embryos.

Biochem/physiol Actions

For dissociation of cultured cells.

Preparation Note

Manufactured by Applied Biotechnology Institute utilizing proprietary transgenic plant protein expression system.

Other Notes

View more information on trypsin at www.sigma-aldrich.com/enzymeexplorer

Legal Information

Trypzean is a registered trademark of ProdiGene, Inc.


pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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K J Mattson et al.
Theriogenology, 69(6), 724-727 (2008-02-19)
The objective was to compare the effects of treating bovine semen with two trypsin products (the porcine pancreas extract and a recombinant) and a control (no trypsin) on in vitro embryo production. Our hypothesis was that the trypsin treatments would
Pedro P Carvalho et al.
Cytotherapy, 13(5), 594-597 (2011-01-05)
Adherent adipose-derived stromal/stem cells (ASC) have been used in pre-clinical regenerative medical studies applied to a broad range of tissues with an ultimate goal of translating these findings to clinical safety and efficacy testing; however, many protocols passage the cells
240 recombinant bovine trypsin made in maize inactivates bovine herpes virus-1 adsorbed to the bovine Zona Pellucida
Seidel, G., et al.
Reproduction, Fertility, and Development, 19, 236-236 (2006)



Global Trade Item Number

SKUGTIN
T3568-100MG04061835559299
T3568-10MG04061832707938