SRP8033
IL-1β mouse
recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)
Synonym(s):
Interleukin-1beta, Postn
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About This Item
biological source
mouse
recombinant
expressed in E. coli
conjugate
untagged
Assay
>95% (SDS-PAGE)
form
lyophilized
mol wt
~17 kDa by SDS-PAGE
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
immunohistochemistry: suitable
impurities
<0.1 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Il1b(16176)
Related Categories
General description
Interleukin-1β (IL-1β) is produced by activated macrophages. It belongs to the IL-1 family of proteins that are involved in the inflammatory response.
Biochem/physiol Actions
Interleukin-1β (IL-1β) stimulates thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation and fibroblast growth factor activity. IL-1β, in most situations requires the inflammasome complex to be cleaved and secreted. This protein may modulate the effects of eosinophils in the intestine.
Physical form
Lyophilized from PBS.
Reconstitution
Reconstitute with 100 μL deionized water.
Other Notes
Mouse IL-1beta (aa 118-269) is untagged.
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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Understanding the mechanism of IL-1? secretion.
Cytokine & Growth Factor Reviews, 22(4), 189-195 (2011)
Drug development research, 83(3), 735-744 (2021-12-21)
Type 2 diabetes mellitus (T2DM) is a metabolic risk factor associated with non-alcoholic liver disease (NAFLD). Schisandrin B (Sch B) is a promising agent for NAFLD. However, the actions of Sch B on diabetes-associated NAFLD and the underlying mechanisms are
IL-1? in eosinophil-mediated small intestinal homeostasis and IgA production.
Mucosal Immunology, 8(4), 930-942 (2015)
Experimental and therapeutic medicine, 23(1), 14-14 (2021-11-25)
Perfluorooctane sulfonate (PFOS) is a persistent pollutant that exerts toxicity and induces cardiogenesis in humans and animals. Yet, the effect of PFOS exposure on cardiac toxicity in adult rats has, to our knowledge, not been reported and the mechanism still
Inflammation, 44(1), 358-370 (2020-10-13)
The inflammatory response involving interleukin-1β (IL-1β) has been thought to play an important role in the development of late-phase sepsis. However, in this study, we wanted to explore the possibility of using IL-1β to improve the prognosis of sepsis by
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