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SML0870

Sigma-Aldrich

LY 2087101

≥98% (HPLC)

Synonym(s):

(2-Amino-5-keto)thiazole), [2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienyl-methanone

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About This Item

Empirical Formula (Hill Notation):
C15H11FN2OS2
CAS Number:
Molecular Weight:
318.39
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

storage condition

(dry room)

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C15H11FN2OS2/c1-9-14(13(19)10-6-7-20-8-10)21-15(17-9)18-12-4-2-11(16)3-5-12/h2-8H,1H3,(H,17,18)

InChI key

PEAMDZVDNYENPN-UHFFFAOYSA-N

Biochem/physiol Actions

LY 2087101 is a selective positive allosteric potentiator of α7 and α4β2 nicotinic acetylcholine receptors (nAChRs). LY 2087101 was shown to not enhance the activity of α3β4 subtype nAChRs.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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