All Photos(1)
Synonym(s):
Ac-LEHD-CHO, caspase 9 inhibitor
Empirical Formula (Hill Notation):
C23H34N6O9
Molecular Weight:
538.55
UNSPSC Code:
12352200
NACRES:
NA.32
Recommended Products
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥80%
storage condition
protect from light
storage temp.
−20°C
Gene Information
human ... CASP9(842)
Amino Acid Sequence
Ac-Leu-Glu-His-Asp-al
Biochem/physiol Actions
Ac-Leu-Glu-His-Asp-al, or Ac-LEHD-CHO, is a cell-permeable tetrapeptide aldehyde. It is an inhibitor of caspase-9. Its target of action has been proposed to be the mitochondrial pathway of apoptosis. Ac-LEHD-CHO has also been postulated to prevent cleavage of caspase-8, and partly to prevent cleavage of caspase-3.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
新产品
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Oncotarget, 8(46), 80770-80789 (2017-11-09)
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