SAB5702163
Anti-STAT6 Antibody, clone 4G7J8, Rabbit Monoclonal
Synonym(s):
D12S1644,IL-4-STAT,STAT6B,STAT6C,STAT6
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
mouse
Technique(s):
immunofluorescence: 1:50 - 1:200, immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000
Application:
IF, IP, WB
Citations:
-
species reactivity
mouse
concentration
0.8 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200, immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
4G7J8, monoclonal
form
liquid
mol wt
100 kDa
Quality Level
Gene Information
human ... STAT6(6778)
General description
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Immunogen
A synthesized peptide derived from human STAT6
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IF/ICC, IP
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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