SAB5702017
[KD Validated]Anti-PCSK9 Antibody, clone 9L4U5, Rabbit Monoclonal
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All Photos(2)
Synonym(s):
FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9
UNSPSC Code:
12352203
NACRES:
NA.46
Recommended Products
biological source
rabbit
Quality Level
material
colorless
clone
9L4U5, monoclonal
form
liquid
species reactivity
human
concentration
1 mg/mL
technique(s)
western blot: 1:500 - 1:1000
color
colorless
isotype
IgG
immunogen sequence
EASIHASCCHAPGLECKVKEHGIPAPQEQVTVACEEGWTLTGCSALPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSEGAVTAVAICCRSRHLAQASQELQ
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PCSK9(255738)
General description
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 593-692 of human Proprotein Convertase 9(PCSK9) (NP_777596.2).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Application
WB
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
WGK
WGK 3
Regulatory Information
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