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About This Item
UNSPSC Code:
12352203
NACRES:
NA.43
biological source
rabbit
Quality Level
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
human, mouse, rat
concentration
2.59 mg/mL
technique(s)
immunohistochemistry: 1:50-1:100
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:1000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pThr261)
Gene Information
human ... MAP2K4(6416)
General description
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
Immunogen
A synthetic phosphorylated peptide around T261 of human MAP2K4 (NP_003001.1).
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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