SAB5500168
Anti-PTEN antibody, Rabbit monoclonal
recombinant, expressed in proprietary host, clone SP170, affinity isolated antibody
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biological source
rabbit
Quality Level
recombinant
expressed in proprietary host
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
SP170, monoclonal
species reactivity
human (tested)
species reactivity (predicted by homology)
dog, mouse
technique(s)
flow cytometry: 1:400
immunoblotting: 1:100
immunohistochemistry: 1:100
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... PTEN(5728)
Related Categories
General description
Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and a member in the PI3K/PTEN/AKT pathway. PTEN is a phosphatase with dual specificity to slow cell growth and antagonize the growth promoting activities from HER protein kinases. The defects of PTEN, mostly around the C-terminus of PTEN, have been implicated in many human cancers and diseases. Therefore, antibody to the N terminus will not be able to detect most of the PTEN protein loss.
Immunogen
Synthetic peptide close to the N-terminus of human PTEN protein.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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