Anti-CD169 antibody, Rabbit monoclonal

CD169 or sialoadhesin is a cell adhesion molecule on the surface of some macrophages distributed in the spleen, liver, lymph node, bone marrow, colon, lung, and various inflammatory tissues. It acts as an endocytic receptor mediating clathrin-dependent endocytosis. CD169 predominately binds to neutrophils, but can also bind to monocytes, natural killer cells, B cells and a subset of cytotoxic T cells by interacting with sialic acid molecules on their surfaces of their ligands.

Synthetic peptide derived from the internal region of human CD169 protein.

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0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

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