SAB5200101
Anti-BSN antibody produced in rabbit
1 mg/mL, affinity isolated antibody
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Synonym(s):
Anti- Neuronal double zine finger protein, Anti-BSN, Anti-Bassoon, Anti-ZNF231
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antigen predicted mol wt 420 kDa
species reactivity
mouse, rat, human
concentration
1 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... BSN(8927)
General description
Bassoon presynaptic cytomatrix protein (BSN) is a 420kDa protein which is expressed in the neuronal synapses. The gene encoding it is located on human chromosome 3p21. The gene ID of the protein is 8927.
Specificity
Detects ~420 kDa, corresponding to the molecular mass of Bassoon. Multiple isoforms can be detected.
Immunogen
NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
Biochem/physiol Actions
Bassoon presynaptic cytomatrix protein (BSN) acts as a scaffold protein and mediates release of neurotransmitters. It is also a part of trafficking and helps in delivery of proteins across the synapse.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
PBS, pH 7..4, 50% glycerol, 0.09% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Product No.
Description
Pricing
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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C Winter et al.
Genomics, 57(3), 389-397 (1999-05-18)
Bassoon is a novel 420-kDa protein recently identified as a component of the cytoskeleton at presynaptic neurotransmitter release sites. Analysis of the rat and mouse sequences revealed a polyglutamine stretch in the C-terminal part of the protein. Since it is
Stefan Hallermann et al.
Neuron, 68(4), 710-723 (2010-11-26)
Sustained rate-coded signals encode many types of sensory modalities. Some sensory synapses possess specialized ribbon structures, which tether vesicles, to enable high-frequency signaling. However, central synapses lack these structures, yet some can maintain signaling over a wide bandwidth. To analyze
Nature, 447(7145), 661-678 (2007-06-08)
There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We describe a joint GWA study (using the Affymetrix GeneChip 500K Mapping Array Set) undertaken in the
Christopher Patzke et al.
Cell, 179(2), 498-513 (2019-10-05)
Neuromodulators bind to pre- and postsynaptic G protein-coupled receptors (GPCRs), are able to quickly change intracellular cyclic AMP (cAMP) and Ca2+ levels, and are thought to play important roles in neuropsychiatric and neurodegenerative diseases. Here, we discovered in human neurons
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