SAB4700298
Monoclonal Anti-HLA-A2 azide free antibody produced in mouse
clone BB7.2, purified immunoglobulin, buffered aqueous solution
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UNSPSC Code:
12352203
NACRES:
NA.41
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biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
BB7.2, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
1 mg/mL
technique(s)
flow cytometry: suitable
immunoprecipitation (IP): suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... HLA-A(3105)
Related Categories
General description
Human leukocyte antigen A α-chain (HLA-A2) is encoded by the gene mapped to human chromosome 6p22.1. HLA-A belongs to the class I molecules of HLa family. The protein structure consists of two polypeptide chains, heavy chain and the non-covalently attached light chain.
The antibody BB7.2 recognizes an epitope at the C-terminus of alpha-2 helix and a turn on one of the underlying beta strands within the human HLA-A2 histocompatibility antigen.
The previously assigned protein identifier P01891 has been merged into P04439. Full details can be found on the UniProt database.
The previously assigned protein identifier P01891 has been merged into P04439. Full details can be found on the UniProt database.
Immunogen
HLA-A2 solubilized by papain
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 5-10 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Biochem/physiol Actions
Human leukocyte antigen A α-chain (HLA-A2) plays a major role in peptide antigen presentation. The encoded protein interacts with cytotoxic T cells (CTL) and facilitates the identification of peptide derived from the influenza matrix protein.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in azide free phosphate buffered saline, pH 7.4; 0.2 um filter sterilized.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Modern vitiligo genetics sheds new light on an ancient disease
Spritz RA
The Journal of Dermatology, 40, 310-318 (2013)
Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2
Gotch F
Nature, 326, 881-882 (1987)
Structure of the human class I histocompatibility antigen, HLA-A2.
Bjorkman PJ
Nature, 329, 506-512 (1987)
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