SAB4700170
Monoclonal Anti-CD38 antibody produced in mouse
clone HIT2, purified immunoglobulin, buffered aqueous solution
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UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
HIT2, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
1 mg/mL
technique(s)
flow cytometry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... CD38(952)
General description
The antibody HIT2 reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells.
Immunogen
Human thymocytes in foetus
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2-8 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Biochem/physiol Actions
Cluster of differentiation 38 (CD38) controls the release of oxytocin hormone that regulates social cognition and affiliative behaviors. CD38 serves as a receptor, an ectoenzyme and acts as a highly conserved calcium-signaling molecule while functioning as a secondary messenger. The generation of cyclic Adenosine diphosphate-ribose and nicotinic acid adenine dinucleotide phosphate from NAD+ and NAD phosphate by ADP-ribosyl cyclase is catalyzed by CD38. The formation of adenosine is an important function of CD38. The pleiotropic nucleoside adenosine formed, acts as a regulator of immune functions and inflammation process.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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ADP ribosyl-cyclases (CD38/CD157), social skills and friendship.
Chong A, et al.
Psychoneuroendocrinology, 78, 185-192 (2017)
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