SAB4504299
Anti-phospho-Casein Kinase II α (pTyr255) antibody produced in rabbit
affinity isolated antibody
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 45 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pTyr255)
Gene Information
human ... CSNK2A1(1457)
General description
Casein kinase II α(CK2) is a pleiotropic serine/threonine kinase, that is located on human chromosome 16p13. 2-p13. 3.
Immunogen
The antiserum was produced against synthesized peptide derived from human Casein Kinase II alpha around the phosphorylation site of Tyr255.
Immunogen Range: 221-270
Immunogen Range: 221-270
Biochem/physiol Actions
Casein kinase II α(CK2) regulates T-cell polarization by initiating the activation of dendritic cells. CK2 participates in the development of breast carcinoma. Mutations in CK2 results in neurodevelopmental abnormalities and dysmorphic features. This protein induces prosurvival and proinflammatory signaling pathways.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
De novo mutations in CSNK2A1 are associated with neurodevelopmental abnormalities and dysmorphic features
Human Genetics, 135(7), 699-705 (2016)
Assignment of the human casein kinase II [alpha][prime] subunit gene (CSNK2A1) to chromosome 16p13. 2-p13. 3
Genomics, 19(1) (1994)
Protein Kinase CK2 Controls the Fate between Th17 Cell and Regulatory T Cell Differentiation
Journal of Immunology, 198(11), 4244-4254 (2017)
Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers
Journal of Leukocyte Biology, 101(3), 703-715 (2017)
CK2?/CSNK2A1 Phosphorylates SIRT6 and Is Involved in the Progression of Breast Carcinoma and Predicts Shorter Survival of Diagnosed Patients
The American Journal of Pathology, 186(12), 3297-3315 (2016)
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