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Key Documents

Safety Information

SAB4504044

Sigma-Aldrich

Anti-phospho-Myosin regulatory light chain 2 (pSer18) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-CMH10, Anti-MFM12, Anti-MLC-2s/v, Anti-MLC2

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10 MG
¥1,831.42

¥1,831.42

Estimated to ship on2025年5月16日Details

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10 MG
¥1,831.42

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

¥1,831.42

Estimated to ship on2025年5月16日Details

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 19 kDa

species reactivity

human, rat, mouse

concentration

~1 mg/mL

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This Item
S9679S4126S2004
Starch from corn practical grade

S4180

Starch from corn

Starch from corn

S9679

Starch from corn

Starch from corn

S4126

Starch from corn

Starch from potato Soluble

S2004

Starch from potato

grade

practical grade

grade

-

grade

-

grade

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

solid

form

solid

form

solid

form

powder

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

useful pH range

4.3 - 6.7

useful pH range

4.0 -7.0

useful pH range

4.0 - 7.0

useful pH range

5.0-7.5 (2% in water)

General description

MYL2 (myosin light chain 2) encodes a myosin regulatory light chain (MLC-2V). It is made of two heavy chains, two essential light chains and two regulatory light chains. It is located on human chromosome 12q24.

Immunogen

The antiserum was produced against synthesized peptide derived from human Myosin regulatory light chain 2 around the phosphorylation site of Ser18.

Immunogen Range: 3-52

Biochem/physiol Actions

MYL2 (myosin light chain 2) helps to convert energy from ATP hydrolysis into mechanical force. This gene also plays a major role in the growth and progression of chronic HF (heart failure). Mutation in MYL2 gene result in infantile type I muscle fibre disease and cardiomyopathy.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    110690

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    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

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    Recessive MYL2 mutations cause infantile type I muscle fibre disease and cardiomyopathy
    Weterman MA, et al.
    Brain (2013)
    Detailed mapping, mutation analysis, and intragenic polymorphism identification in candidate Noonan syndrome genes MYL2,DCN, EPS8, andRPL6
    ION A, et al.
    Journal of medical Genetics, 37(11), 884-886 (2000)
    Slow cardiac myosin regulatory light chain 2 (MYL2) was down-expressed in chronic heart failure patients
    Li Y, et al.
    Clinical Cardiology, 34(1), 30-34 (2011)

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