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Key Documents

Safety Information

SAB4503583

Sigma-Aldrich

Anti-CD4 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 precursor

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20 PKG
CN¥722.66

CN¥722.66

Estimated to ship onJune 30, 2025Details

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20 PKG
CN¥722.66

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

CN¥722.66

Estimated to ship onJune 30, 2025Details

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 51 kDa

species reactivity

human, mouse

concentration

~1 mg/mL

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Sucrose Molecular Biology Grade

573113

Sucrose

biological source

bakers yeast

biological source

-

biological source

Saccharomyces cerevisiae

biological source

-

form

solid

form

solid

form

lyophilized powder

form

solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

15-25°C

foreign activity

α-galactosidase (melibiase) ≤0.01%

foreign activity

α-galactosidase (melibiase), essentially free

foreign activity

-

foreign activity

DNases, proteases, RNases, none detected

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

General description

Anti-CD4 Antibody detects endogenous levels of total CD4 protein.
CD4 (CD4 molecule) is present in the surface of specific leukocytes. CD4 contains four ecto-domains (D1-D4) of which D1, D2, and D4 contain disulfide bonds. It is mapped to human chromosome 12p13.31.

Immunogen

The antiserum was produced against synthesized peptide derived from human CD4.

Immunogen Range: 401-450

Application

Anti-CD4, C-Terminal antibody has been used in immunohistochemical staining.

Biochem/physiol Actions

CD4 (CD4 molecule) helps in the activation of immunostimulatory T-cells. It serve as a primary receptor for HIV-1 entry.This molecule plays an important role on cell membrane mechanical characteristics and can be used in the development of cell biology and medicine.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

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    Certificates of Analysis (COA)

    Lot/Batch Number
    210846

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    M I Ashraf et al.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 16(3), 808-820 (2015-11-26)
    Lipocalin 2 (Lcn2) is rapidly produced by damaged nephron epithelia and is one of the most promising new markers of renal injury, delayed graft function and acute allograft rejection (AR); however, the functional importance of Lcn2 in renal transplantation is
    Fang Zhang et al.
    Frontiers in immunology, 10, 2392-2392 (2019-11-05)
    Background: Stroke patients with diabetes suffer from higher mortality rate and worsened neurological outcome. However, the responses of immune system to cerebral ischemia in the setting of diabetes remain poorly understood. Methods: In this study, we investigated the temporal profile
    Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation
    Ashraf MI, et al.
    American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 16(3), 808-820 (2016)
    Human CD4 Metastability Is a Function of the Allosteric Disulfide Bond in Domain 2
    Owen GR, et al.
    Biochemistry, 55(15), 2227-2237 (2016)
    The role of CD4 on mechanical properties of live cell membrane
    Bui VC and Nguyen TH
    Journal of Biomedical Materials Research Part A, 104(1), 239-244 (2016)
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