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Merck
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SAB4503363

Anti-ACSS1 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Acetate--CoA ligase 2, Acetyl-CoA synthetase 2, Acetyl-coenzyme A synthetase 2-like, Acyl-CoA synthetase short-chain family member 1

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
immunohistochemistry
western blot
Species reactivity:
human, mouse
Citations:
3
Technique(s):
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
Uniprot accession no.:
Q9NUB1

Key Documents

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Product Name

Anti-ACSS1 antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 74 kDa

species reactivity

human, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

Q9NUB1

UniProt accession no.

Q9NUB1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... ACSS1(84532)

Biochem/physiol Actions

Acetyl coenzyme A (CoA) synthetase 1 (ACSS1) participates in the oxidation of acetate. It converts acetate to acetyl-CoA in an ATP-dependent reaction. ACSS1 promotes aggressive tumor growth.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Anti-ACSS1 Antibody detects endogenous levels of total ACSS1 protein.
Acetyl coenzyme A (CoA) synthetase 1 (ACSS1) is an enzyme which is also termed as Acecs2. It is present in the mitochondria. It is located on human chromosome 20p11.21.

Immunogen

The antiserum was produced against synthesized peptide derived from human ACSS1.

Immunogen Range: 611-660

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
3114234

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Jagged1 DNA Copy Number Variation Is Associated with Poor Outcome in Liver Cancer.
Kawaguchi K, et al.
The American Journal of Pathology, 186(8), 2055-2067 (2016)
Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth.
Lakhter AJ, et al.
The Journal of Biological Chemistry, 291(42), 21869-21879 (2016)
Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate.
Fujino T, et al.
The Journal of Biological Chemistry, 276(14), 11420-11426 (2001)

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