SAB4502956
Anti-TGF β2, C-Terminal antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Cetermin, G-TSF, Polyergin, TGFB2, Transforming growth factor β-2
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
immunohistochemistry
immunohistochemistry
Species reactivity:
mouse, rat, human
Citations:
3
Technique(s):
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
immunohistochemistry: 1:50-1:100
Uniprot accession no.:
Product Name
Anti-TGF β2, C-Terminal antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 47 kDa
species reactivity
mouse, rat, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
NCBI accession no.
UniProt accession no.
application(s)
research pathology
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TGFB2(7042)
Application
Anti-TGF β2, C-Terminal antibody produced in rabbit has been used in western blotting.
Biochem/physiol Actions
Transforming growth factor-β2 (TGFB2) protein plays a key role in transforming growth factor-β (TGF-β) signaling pathway. It aids in binding several TGF-β receptors to recruit and stimulate the others against decapentaplegic homolog SMAD protein family. TGF-β2 is involved in the proliferation and metastasis of glioma cells. It is implicated in metabolic syndrome (MetS). Single-nucleotide polymorphisms (SNPs) in TGFB2 are also associated with end-stage renal disease and conotruncal heart defects.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
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General description
Anti-TGF β2 Antibody detects endogenous levels of total TGF β2 protein.
Transforming growth factor-β2 (TGFB2) gene codes for the transforming growth factor β2 (TGFβ2).( β (TGF-β) protein superfamily. TGFB2 gene is mapped to human chromosome 1q41.
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta2.
Immunogen Range: 361-410
Immunogen Range: 361-410
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Mustafa Becerikli et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 40(8), 1810-1826 (2021-11-15)
Bone regeneration and fracture healing are impaired in diabetic patients due to defective functions of associated cells. Thus, the search for molecular causes and new treatment strategies are of particular clinical relevance. We investigated the gene expression profile of bones
Eugene Lin et al.
Scientific reports, 7(1), 13589-13589 (2017-10-21)
The transforming growth factor-β (TGF-β) signaling pathway and its relevant genes have been correlated with an increased risk of developing various hallmarks of metabolic syndrome (MetS). In this study, we assessed whether the TGF-β signaling pathway-associated genes of SMAD family
Kejuan Song et al.
Oncology reports, 39(5), 2063-2070 (2018-03-08)
Ovarian cancer is a highly metastatic malignancy and a leading cause of cancer-related death in postmenopausal women. Emodin is a natural anthraquinone isolated from several traditional Chinese medicines including Rhubarb and Polygonum cuspidatum. Recently, emodin was demonstrated to reduce the growth
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