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Merck
CN

SAB4502489

Anti-Parathyroid Hormone antibody produced in rabbit

affinity isolated antibody

Synonym(s):

PTH/PTHr receptor, PTH/PTHrP type I receptor, PTHR1, Parathyroid hormone/parathyroid hormone-related peptide receptor precursor

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD01324156

Key Documents

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Product Name

Anti-Parathyroid Hormone antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 12 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:10000
western blot: 1:500-1:1000

NCBI accession no.

P01270

UniProt accession no.

P01270

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... PTH(5741)

Related Categories

Biochem/physiol Actions

PTH (parathyroid hormone) significantly maintains calcium and phosphate homeostasis. The function of PTH is brought about by PTH receptor, a G protein-coupled receptor. Upregulation of PTH is observed in hyperparathyroidism, which leads to hypertension, bone and cardiovascular disease. PTH is also known to improve fracture healing.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Anti-Parathyroid Hormone antibody detects endogenous levels of total parathyroid hormone protein.
The PTH (parathyroid hormone) gene is mapped to human chromosome 11p15.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human Parathyroid Hormone.

Immunogen Range: 51-100

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
310293

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Effects of parathyroid hormone 1-34 on osteogenic and chondrogenic differentiation of human fracture haematoma-derived cells in vitro.
Dogaki Y
Journal of Tissue Engineering and Regenerative Medicine, 10(10), E365-E371 (2016)
Parathyroid pathology: hyperparathyroidism and parathyroid tumors.
Carlson D
Archives of Pathology & Laboratory Medicine, 134(11), 1639-1644 (2010)
Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport.
Sneddon WB
The Journal of Biological Chemistry, 291(36), 18632-18642 (2016)
Genetic Variants Associated with Circulating Parathyroid Hormone.
Robinson-Cohen C
Journal of the American Society of Nephrology, 28(5), 1553-1565 (2017)

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