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Key Documents

Safety Information

SAB4502260

Sigma-Aldrich

Anti-PPAR-α antibody produced in rabbit

affinity isolated antibody

Synonym(s):

NR1C1, PPAR-α, PPARA Peroxisome proliferator-activated receptor α

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100 μG
¥4,842.58

¥4,842.58

Estimated to ship on2025年9月10日Details

New, lower price on this item!
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100 μG
¥4,842.58

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

¥4,842.58

Estimated to ship on2025年9月10日Details

New, lower price on this item!

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 52 kDa

species reactivity

human, rat, mouse

concentration

~1 mg/mL

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Anti-PPAR-α antibody produced in rabbit affinity isolated antibody

SAB4502260

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Anti-PPARA antibody produced in rabbit affinity isolated antibody

SAB2101852

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Anti-PPARA antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody

HPA058901

Anti-PPARA antibody produced in rabbit

Anti-PPARA antibody produced in mouse purified immunoglobulin, buffered aqueous solution

SAB1406277

Anti-PPARA antibody produced in mouse

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

dry ice

General description

Anti-PPAR-α antibody detects endogenous levels of total PPAR-α protein.
The PPAR-α (peroxisome proliferator-activated receptor α) gene is mapped to human chromosome 22q13.31. Ppar-α is localized to the nucleus.

Immunogen

The antiserum was produced against synthesized peptide derived from human PPAR-alpha.

Immunogen Range: 6-55

Biochem/physiol Actions

PPAR-α (peroxisome proliferator-activated receptor α) is a receptor transcription factor that inhibits inflammation, by preventing the nuclear factor κB activation. Omega-3 long-chain polyunsaturated fatty acids is known to be the ligand that brings out the anti-inflammatory action of Ppar-α. Ppar-α is involved in epidermal proliferation and differentiation and therefore serves as a skin barrier. PPARα mediates lipid metabolism by inducing fatty acid oxidation and also regulates glucose metabolism. Variation in the gene is observed in schizophrenia.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品
  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    210975

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    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

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    Eupatilin with PPAR? agonistic effects inhibits TNF?-induced MMP signaling in HaCaT cells.
    Jung Y
    Biochemical and Biophysical Research Communications, 493(1), 220-226 (2017)
    Role of PPAR? in the attenuation of bile acid-induced apoptosis by omega-3 long-chain polyunsaturated fatty acids in cultured hepatocytes.
    Tillman EM
    Pediatric Research, 79(5), 754-758 (2016)
    Microdeletions involving chromosomes 12 and 22 associated with syndromic Duane retraction syndrome.
    Abu-Amero KK
    Ophthalmic Genetics, 35(3), 162-169 (2014)
    An association between the PPAR?-L162V polymorphism and nicotine dependency among patients with schizophrenia.
    Nadalin S
    Comprehensive Psychiatry, 70, 118-124 (2016)
    Nutrient-sensing nuclear receptors PPAR? and FXR control liver energy balance.
    Preidis GA
    The Journal of Clinical Investigation, 127(4), 1193-1201 (2017)
    View All Related Papers

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