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SAB4502048

Sigma-Aldrich

Anti-OPRM1 antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
MOR, MUOR1, Mu-type opioid receptor, OPRM, OPRM1
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 44 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... OPRM(4988)

General description

Anti-OPRM1 Antibody detects endogenous levels of total OPRM1 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human OPRM1.

Immunogen Range: 21-70

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Marcel M Wygas et al.
International journal of molecular sciences, 24(15) (2023-08-12)
Many peptide-activated rhodopsin-like GPCRs share a β-hairpin folding motif in the extracellular loop 2 (ECL2), which interacts with the peptide ligand while at the same time being connected to transmembrane helix 3 (TM3) via a highly conserved disulfide bond. Currently
Florence R M Theberge et al.
Psychopharmacology, 224(4), 559-571 (2012-07-14)
Responding to heroin cues progressively increases after cessation of heroin self-administration (incubation of heroin craving). We investigated whether this incubation is associated with time-dependent changes in brain-derived neurotrophic factor (BDNF) and methyl-CpG binding protein 2 (MeCP2) signaling and mu opioid

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