Skip to Content

很抱歉，目前系统维护中。在此期间，网站下单功能无法使用。给您带来不便，深表歉意。如需其他帮助，请联系客户联络中心：400 620 3333。

Merck
CN
All Photos(3)

Key Documents

Safety Information

SAB4501984

Sigma-Aldrich

Anti-NRF2 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

HEBP1, NF-E2 related factor 2, NF2L2, NFE2-related factor 2, NFE2L2

Sign Into View Organizational & Contract Pricing

Select a Size

500 μL
CN¥4,489.38

CN¥4,489.38

Estimated to ship onMay 26, 2025Details

All Photos(3)

Select a Size

Change View
500 μL
CN¥4,489.38

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

CN¥4,489.38

Estimated to ship onMay 26, 2025Details

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 67 kDa

species reactivity

rat, mouse, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
A2052AB175PC213L
Anti-GABA (No Gluteraldehyde) Antibody Chemicon®, from rabbit

AB5016

Anti-GABA (No Gluteraldehyde) Antibody

Anti-GABA antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

A2052

Anti-GABA antibody produced in rabbit

Anti-GABA Antibody serum, Chemicon®

AB175

Anti-GABA Antibody

Anti-GABA Rabbit pAb lyophilized, Calbiochem®

PC213L

Anti-GABA Rabbit pAb

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

serum

antibody form

serum

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

Gene Information

rat ... Gabra1(29705)

Gene Information

rat ... Gabra1(29705)

Gene Information

rat ... Gabra1(29705)

Gene Information

rat ... Gabra1(29705)

shipped in

wet ice

shipped in

dry ice

shipped in

dry ice

shipped in

ambient

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

General description

Anti-NRF2 Antibody detects endogenous levels of total NRF2 protein.
NRF2 (nuclear factor, erythroid 2 like 2) gene is mapped to human chromosome 2q31.2. The encoded protein is localized to dendritic cells. It belongs to the cap ′n′ collar (CNC) family of transcription factors.

Immunogen

The antiserum was produced against synthesized peptide derived from human Nrf2.

Immunogen Range: 556-605

Application

Anti-NRF2, C-Terminal antibody produced in rabbit has been used in western blotting analysis.[1][2]

Biochem/physiol Actions

Nrf2 (nuclear factor, erythroid 2 like 2) is involved in the regulation of anti-oxidative and anti-inflammatory response. The protein encoded is a transcription factor that binds to the antioxidant response element of the target gene. In response to oxidative stress, Nrf2 upregulates the enzymes associated with detoxification, anti-inflammation, cytoprotection and antioxidative pathways. Nrf2 affects glucose metabolism and ROS (reactive oxygen species) homeostasis in cancer cells by regulating the pentose phosphate pathway. Thus, Nrf2 is known to contribute to the development of cancer by promoting cell proliferation.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    424170279
    310279

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Xin Liu et al.
    Biochimica et biophysica acta, 1863(8), 2093-2103 (2016-05-18)
    The cap 'n' collar (CNC) family of transcription factors play important roles in resistance of oxidative and electrophilic stresses. Among the CNC family members, NF-E2-related factor 2 (Nrf2) is critical for regulating the antioxidant and phase II enzymes through antioxidant
    Martin Adam et al.
    International journal of cardiology, 228, 341-346 (2016-11-21)
    Overweight has been associated with an increase in inflammatory markers and with an imbalance in the autonomic nervous system, such as a decrease in heart rate variability (HRV). In this study we aimed to investigate the modifying effect of a
    Daihong Cao et al.
    Molecular medicine reports, 25(6) (2022-04-28)
    It has been reported that oxidative stress plays a prominent role in diabetic macrovascular diseases. 3,4‑Dihydroxyacetophenone (3,4‑DHAP) has been found to have a variety of biological activities. However, few studies have assessed the antioxidant capacity of 3,4‑DHAP and the underlying
    Jialiang Wang et al.
    Experimental cell research, 360(2), 66-73 (2017-08-08)
    Nrf2 is presented in dendritic cells (DCs) and contributes to the maintenance of redox homeostasis. However, the expression pattern and function of Nrf2 in the maturation of DCs in the glioma-infiltrated microenvironment remain unrevealed. Our study aims to investigate the
    Lingli Hu et al.
    Experimental and therapeutic medicine, 20(1), 283-292 (2020-06-20)
    Glucocorticoids (GCs) exert a therapeutic effect in numerous chronic inflammatory diseases. However, chronic obstructive pulmonary disease (COPD) tends to be GC-resistant. Icariin, a major component of flavonoids isolated from Epimedium brevicornum Maxim (Berberidaceae), significantly relieves symptoms in patients with COPD.
    View All Related Papers

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service