SAB4501220
Anti-GLP1R antibody produced in rabbit
affinity isolated antibody
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GLP-1 receptor, GLP-1-R, GLP-1R, GLP1R, Glucagon-like peptide 1 receptor
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 53 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000
immunofluorescence: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... GLP1R(2740)
General description
Anti-GLP1R Antibody detects endogenous levels of total GLP1R protein.
Glucagon-like peptide 1 receptor (GLP1R) protein belongs to the class B G protein-coupled receptor (GPCR) secretin family. This classic seven-transmembrane protein is abundantly expressed in the cardiovascular system. The GLP1R gene is located on the human chromosome 6p21. Anti-GLP1R Antibody detects endogenous levels of total GLP1R protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human GLP1R.
Immunogen Range: 101-150
Immunogen Range: 101-150
Application
Anti-GLP1R antibody produced in rabbit has been used in immunofluorescence staining.
Biochem/physiol Actions
Glucagon-like peptide 1 receptor (GLP1R) protein participates in the activation of protein kinase A (PKA), phosphoinositide 3-kinase (PI3K), MEK1/2, and endothelial nitric oxide synthase (eNOS) pathways. Hence, it plays a key role in apoptosis reduction, improved energy metabolism, decreased inflammation in myocardial cells, and vasodilation in myocardial arteries. The large N-terminal extracellular domain of GLP1R participates in ligand binding. Alterations in the GLP1R gene might increase the risk of coronary artery disease (CAD).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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Journal of diabetes research, 2018, 1054192-1054192 (2018-10-03)
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