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Key Documents

Safety Information

SAB4500989

Sigma-Aldrich

Anti-FOLR1 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

FR-α, Folate receptor, Folate receptor α, Folate receptor 1, adult

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100 μG
CN¥5,187.66

CN¥5,187.66

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100 μG
CN¥5,187.66

About This Item

MDL number:
MFCD02262889
UNSPSC Code:
12352203
NACRES:
NA.41

CN¥5,187.66

Please contact Customer Service for Availability

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 29 kDa

species reactivity

rat, mouse, human

concentration

~1 mg/mL

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Anti-FOLR1 antibody produced in rabbit affinity isolated antibody

SAB4500989

Anti-FOLR1 antibody produced in rabbit

Anti-FOLR1 antibody produced in rabbit purified immunoglobulin, buffered aqueous solution

SAB1410427

Anti-FOLR1 antibody produced in rabbit

Anti-FOLH1 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

HPA010593

Anti-FOLH1 antibody produced in rabbit

Anti-OLR1 antibody produced in rabbit IgG fraction of antiserum

AV45322

Anti-OLR1 antibody produced in rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

IgG fraction of antiserum

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

UniProt accession no.

P15328

UniProt accession no.

P15328

UniProt accession no.

Q04609

UniProt accession no.

P78380

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

The folate receptor 1 (FOLR1) gene encodes for folate receptor α protein, a membrane-bound glycoprotein. The FOLR1 gene is mapped on the human chromosome at 11q13.4. Anti-FOLR1 antibody detects endogenous levels of total FOLR1 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human FOLR1.

Immunogen Range: 41-90

Biochem/physiol Actions

Folate receptor α protein binds and facilitates the transport of folate into the cells. This protein acts as a therapeutic target as well as a prognostic marker for various kinds of cancers. Upregulation of the FOLR1 gene is associated with ovarian, lung, breast, brain, colorectal, and gastric cancers.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    3115761

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    Find documentation for the products that you have recently purchased in the Document Library.

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    Michelle R O'Byrne et al.
    Birth defects research. Part A, Clinical and molecular teratology, 88(8), 689-694 (2010-08-05)
    Meningomyelocele (MM) results from lack of closure of the neural tube during embryologic development. Periconceptional folic acid supplementation is a modifier of MM risk in humans, leading toan interest in the folate transport genes as potential candidates for association to
    Yuan Yuan et al.
    Human pathology, 40(10), 1453-1460 (2009-05-21)
    The objective of this study was to analyze the diagnostic and clinical role of the folate receptor-alpha (FOLR1) and folate receptor-gamma (FOLR3) genes in effusion cytology. Expression of the FOLR1 protein product, FR-alpha, was additionally studied. Ninety-one effusions (71 ovarian
    Correction: Folate receptor-α (FOLR1) expression and function in triple negative tumors.
    Brian M Necela et al.
    PloS one, 10(4), e0127133-e0127133 (2015-05-01)
    Minsung Kim et al.
    PloS one, 13(6), e0198347-e0198347 (2018-06-07)
    Gastric cancer is a malignancy that has a high mortality rate. Although progress has been made in the treatment of gastric cancer, many patients experience cancer recurrence and metastasis. Folate receptor 1 (FOLR1) is overexpressed on the cell surface in

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