SAB4500577
Anti-ADRB2 antibody produced in rabbit
affinity isolated antibody
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ADRBR, B2AR, BAR, BETA2AR, β-2 adrenergic receptor, β-2 adrenoceptor, β-2 adrenoreceptor, ADRB2, ADRB2R
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 46 kDa
species reactivity
human, rat, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ADRB2(154)
General description
Anti-ADRB2 Antibody detects endogenous levels of total ADRB2 protein.
Adrenoceptor β 2/β2 adrenergic receptor (ADRB2), a transmembrane protein, belongs to the superfamily of G-protein coupled receptors (GPCRs). This protein is expressed in skeletal muscle, mast cells, lymphocytes, airway smooth muscle, epithelial and endothelial cells of the lung, the smooth muscle of blood vessels, oral and skin keratinocytes. It comprises seven transmembrane domains and three extracellular and three intracellular loops. ADRB2 gene is located on human chromosome 5q32. Anti-ADRB2 Antibody detects endogenous levels of total ADRB2 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human ADRB2.
Immunogen Range: 201-250
Immunogen Range: 201-250
Biochem/physiol Actions
Adrenoceptor β 2/β2 adrenergic receptor (ADRB2) binding to agonist activates Gs protein. Variation in the ADRB2 gene is involved in blood pressure (BP) and body mass index (BMI). ADRB2 is associated with nasopharyngeal carcinoma.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
ADRB2 (adrenoceptor beta 2, surface)
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2021)
The American journal of physiology, 276(4), H1379-H1384 (1999-04-13)
Glucocorticoids and catecholamines exert important effects on cardiovascular physiology and metabolism. Variants of the glucocorticoid receptor gene (GRL) and the beta2-adrenergic receptor gene (ADRB2) have been associated with high blood pressure and obesity. These genes are close on human chromosome
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