Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
species reactivity
human
technique(s)
immunohistochemistry: 1:20-1:100
accession no.
NP_057196
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PKD2L1(9033)
General description
PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel) is also known as polycystin-L/ transient receptor potential polycystin-3 (TRPP3). It is expressed in brain, kidney, heart, skeletal muscle, spleen, testis, retina and in the bipolar neurons in the tongue taste buds. TRPP3 is present on the surface membrane and/or endoplasmic reticulum membrane of cells. It belongs to the PKD2 gene family. PKD2L1 is mapped to human chromosome 10q25.
Immunogen
Synthetic peptide of human PKD2L1
Biochem/physiol Actions
PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel) participates in hedgehog signaling, intestinal development and sour tasting. It controls ciliary Ca2+ concentration. Mutations in PKD2 results in autosomal dominant kidney disease (ADPKD).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
新产品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Identification ofPKD2L, a HumanPKD2-Related Gene: Tissue-Specific Expression and Mapping to Chromosome 10q25.
Wu G, et al.
Genomics, 54(3), 564-568 (1998)
Regulation of TRPP3 channel function by N-terminal domain palmitoylation and phosphorylation.
Zheng W, et al.
The Journal of Biological Chemistry, 291(49), 25678-25691 (2016)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service