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SAB4301564

Sigma-Aldrich

Anti-phospho-ROCK2 (pTyr722) antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
ROCK-II
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

160 kDa

species reactivity

human, mouse, rat

concentration

1.0 mg/mL

technique(s)

western blot: 1:500-1:1000 (Cell Lysate)

isotype

IgG

accession no.

NP_033098.2

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr722)

Gene Information

mouse ... Rock2(19878)

Specificity

The antibody detects endogenous level of ROCK2 only when phosphorylated at Tyrosine 722.

Immunogen

Peptide sequence around phosphorylation site of Tyrosine 722(K-I-Y(p)-E-S) derived from Human ROCK2.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Dylan R Addis et al.
American journal of physiology. Lung cellular and molecular physiology, 319(2), L337-L359 (2020-06-25)
Bromine (Br2) is an organohalide found in nature and is integral to many manufacturing processes. Br2 is toxic to living organisms, and high concentrations can prove fatal. To meet industrial demand, large amounts of purified Br2 are produced, transported, and
Manhua Xu et al.
Heliyon, 9(11), e22012-e22012 (2023-12-04)
To investigate the effect and potential molecular mechanism of microRNA-93 (miR-93) on retinal ganglion cells (RGCs) apoptosis as well as retinal damage in acute glaucoma mice. RGCs apoptosis were induced by oxygen-glucose deprivation and reperfusion (OGD/R). The pro-apoptotic effect of

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