SAB4300684
Anti-phospho-Cyclin E1 (pThr395) antibody produced in rabbit
affinity isolated antibody
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Synonym(s):
Anti-CCNE, Anti-CCNE1
UNSPSC Code:
12352203
NACRES:
NA.41
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~48 kDa
species reactivity
human
concentration
1 mg/mL
technique(s)
western blot: 1:500-1:1000
isotype
IgG
immunogen sequence
(L-L-Tp-P-P)
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pThr395)
Gene Information
human ... CCNE1(898)
General description
The antibody detects endogenous level of Cyclin E1 only when phosphorylated at threonine 395.
Immunogen
Peptide sequence around phosphorylation site of threonine 395 (L-L-Tp-P-P), according to the protein NP_001229.1
Features and Benefits
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Target description
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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