SAB4300674
Anti-phospho-Tyrosine Hydroxylase (pSer31) antibody produced in rabbit
affinity isolated antibody
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Synonym(s):
Anti-TH, Anti-Tyrosine 3-hydroxylase, Anti-Tyrosine 3-monooxygenase
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
55-60 kDa
species reactivity
rat, human, mouse
concentration
1 mg/mL
technique(s)
western blot: 1:500-1:1000
isotype
IgG
immunogen sequence
(V-T-Sp-P-R)
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer31)
Gene Information
human ... TH(7054)
General description
The antibody detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at serine 31.
Immunogen
Peptide sequence around phosphorylation site of serine31 (V-T-Sp-P-R), according to the protein NP_000351.2
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Target description
Plays an important role in the physiology of adrenergic neurons.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Alán Alpár et al.
The EMBO journal, 37(21) (2018-09-14)
Stress-induced cortical alertness is maintained by a heightened excitability of noradrenergic neurons innervating, notably, the prefrontal cortex. However, neither the signaling axis linking hypothalamic activation to delayed and lasting noradrenergic excitability nor the molecular cascade gating noradrenaline synthesis is defined.
Rita Matuska et al.
Brain structure & function, 225(3), 969-984 (2020-03-23)
Chronic hypernatremia activates the central osmoregulatory mechanisms and inhibits the function of the hypothalamic-pituitary-adrenal (HPA) axis. Noradrenaline (NE) release into the periventricular anteroventral third ventricle region (AV3V), the supraoptic (SON) and hypothalamic paraventricular nuclei (PVN) from efferents of the caudal
Scot McIntosh et al.
Frontiers in psychiatry, 4, 88-88 (2013-08-24)
Chronic cocaine administration regulates the expression of several proteins related to dopaminergic signaling and synaptic function in the mesocorticolimbic pathway, including the prefrontal cortex. Functional abnormalities in the prefrontal cortex are hypothesized to be due in part to the expression
András H Lékó et al.
Scientific reports, 7(1), 3396-3396 (2017-06-15)
Adaptation to motherhood includes maternal behaviour and lactation during the postpartum period. The major organizing centres of maternal behaviour and lactation are located in the hypothalamic medial preoptic area (MPOA) and the arcuate nucleus, respectively. Insulin-like growth factor I (IGF-I)
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