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Merck
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SAB4300250

Anti-phospho-SMAD1 (pSer465) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-BSP1 antibody produced in rabbit, Anti-JV4-1 antibody produced in rabbit, Anti-JV41 antibody produced in rabbit, Anti-MADH1 antibody produced in rabbit, Anti-SMAD family member 1 antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~55 kDa

species reactivity

mouse, rat, human

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(I-S-S-V-SP)

NCBI accession no.

NP_001003688.1

UniProt accession no.

Q15797

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer465)

Gene Information

human ... SMAD1(4086)

Related Categories

General description

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).

Immunogen

Peptide sequence around phosphorylation site of serine 465 (I-S-S-V-S(p)), according to the protein SMAD1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
951411321

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Xin-Yue Zhang et al.
Cellular signalling, 55, 109-118 (2019-01-12)
Bone morphogenetic protein 6 (BMP6) and transforming growth factor-β1 (TGF-β1) are key intraovarian regulators that play essential roles in regulating mammalian follicular function and promoting oocyte maturation. Furin, a member of the subtilisin-like proprotein convertase family, promotes the activation of
Raquel Escrich et al.
The Journal of nutritional biochemistry, 64, 218-227 (2018-12-21)
Breast cancer is the most common malignancy in women worldwide, and dietary lipids are important environmental factors influencing its etiology. We have investigated the effects, and the mechanisms associated, of high-fat diets on 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors. Animals were fed
Chao-Ming Chen et al.
Cryobiology, 89, 82-89 (2019-05-09)
Recycled autografts have been commonly used in biological reconstruction in conjunction with wide bone resection. Extracorporeal irradiation (ECIR) and freezing are the two major options for pretreating tumor-bearing autografts before transplant. This study, for the first time, compared the effects
Jinghua Gui et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(10), 4352-4361 (2019-02-15)
At the level of organ formation, tissue morphogenesis drives developmental processes in animals, often involving the rearrangement of two-dimensional (2D) structures into more complex three-dimensional (3D) tissues. These processes can be directed by growth factor signaling pathways. However, little is
Ken Shimizu et al.
Journal of assisted reproduction and genetics, 36(6), 1185-1194 (2019-05-13)
Follicle-stimulating hormone receptor (FSHR) expression in granulosa cells is critical in enabling follicles to achieve accelerated growth. Although FSHR expression has been reported to be epigenetically regulated, the mechanism is unclear. Cooperation between oocytes and granulosa cells is also essential
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