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SAB4300047

Anti-phospho-PTK2 (pTyr861) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-FADK antibody produced in rabbit, Anti-FAK antibody produced in rabbit, Anti-FAK1 antibody produced in rabbit, Anti-PTK2 protein tyrosine kinase 2 antibody produced in rabbit, Anti-pp125FAK antibody produced in rabbit

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-phospho-PTK2 (pTyr861) antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~125 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(H-I-YP-Q-P)

NCBI accession no.

NP_005598.3

UniProt accession no.

Q05397

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr861)

Gene Information

human ... PTK2(5747)

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General description

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

Immunogen

Peptide sequence around phosphorylation site of tyrosine 861 (H-I-Y(p)-Q-P), according to the protein PTK2.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
511711059

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