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SAB3500597

Sigma-Aldrich

Anti-ZIP6 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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Synonym(s):
Anti-LIV-1, Anti-SLC39A6, Anti-Slc39A6, Anti-Solute carrier family 39 member A6
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human

technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

NCBI accession no.

NP_001092876

UniProt accession no.

Q13433

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SLC39A6(25800)

General description

ZIP6 is encoded by SLC39A6 (solute carrier family 39 member 6) gene. The gene has ten exons and 20864 bases. It is a multi-pass membrane protein and has a molecular weight of 85 kDa. ZIP6 is expressed at high levels in normal breast tissue, prostate, placenta, kidney, pituitary and corpus callosum. This gene is located on human chromosome 18q12.2.

Immunogen

ZIP6 antibody was raised against a 16 amino acid peptide near the center of human ZIP6.

Biochem/physiol Actions

ZIP6 (ZIP metal ion transporter family) controls the expression level of E-cadherin. It serves as a zinc influx transporter. SLC39A6 participates in the cellular invasion of HeLa cells by modulating the snail and slug expression mediated by ERK (extracellular signal–regulated kinase).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500597.

Physical form

Supplied in PBS with 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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SLC39A6 (solute carrier family 39 (zinc transporter), member 6)
Hamada S, et al.
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2011)

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