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Key Documents

Safety Information

SAB2700645

Sigma-Aldrich

Anti-Ehmt2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Bat8, D17Ertd710e, EHMT2, G9a

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse

technique(s)

western blot: 1:500-1:3000

NCBI accession no.

NP_665829

UniProt accession no.

Q9Z148

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Ehmt2(110147)

Immunogen

Recombinant fragment corresponding to a region within amino acids 657 and 1021 of G9a according to NP_665829

Application

Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Biochem/physiol Actions

Histone methyltransferase. Preferentially methylates ′Lys-9′ of histone H3 and ′Lys-27′ of histone H3 (in vitro). H3 ′Lys-9′ methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also methylates histone H1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Disclaimer

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
GT40296

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Carlos Wilson et al.
Cell reports, 31(6), 107639-107639 (2020-05-14)
The generation of axonal and dendritic domains is critical for brain circuitry assembly and physiology. Negative players, such as the RhoA-Rho coiled-coil-associated protein kinase (ROCK) signaling pathway, restrain axon development and polarization. Surprisingly, the genetic control of neuronal polarity has
Ana Fiszbein et al.
Cell reports, 14(12), 2797-2808 (2016-03-22)
Chromatin modifications are critical for the establishment and maintenance of differentiation programs. G9a, the enzyme responsible for histone H3 lysine 9 dimethylation in mammalian euchromatin, exists as two isoforms with differential inclusion of exon 10 (E10) through alternative splicing. We

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