SAB2501668
Anti-UCHL1 (C-terminal) antibody produced in goat
affinity isolated antibody, buffered aqueous solution
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Synonym(s):
PARK5, PGP9.5, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
goat
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
canine, bovine, rat, rabbit, pig, human
technique(s)
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... UCHL1(7345)
General description
Ubiquitin C-terminal hydrolase L1 (UCHL1) is a deubiquitinase which is part of the ubiquitin proteasome system (UPS). The protein is expressed in the nervous system and gonads. The gene encoding UCHL1 is localized on human chromosome 4p13.
Immunogen
Peptide with sequence EVRFSAVALCK, from the C-terminal region of the protein sequence according toNP_004172.2
Biochem/physiol Actions
Ubiquitin C-terminal hydrolase L1 (UCHL1) has a role in epithelial-mesenchymal transition. It also has roles in invasion and in the cell cycle. UCHL1 catalyzes the hydrolysis of carboxy-terminal ubiquitin esters and amides. The protein has been associated with various cancers.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Product No.
Description
Pricing
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Ubiquitin carboxyl-terminal esterase L1 (UCHL1) is associated with stem-like cancer cell functions in pediatric high-grade glioma.
Sanchez-diaz PC
PLoS ONE (2017)
UCH-LI acts as a novel prognostic biomarker in gastric cardiac adenocarcinoma.
YAng H
International Journal of Clinical and Experimental Pathology (2015)
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