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Key Documents

Safety Information

SAB2501553

Sigma-Aldrich

Anti-Itga11 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-4732459H24Rik, Anti-Itga11, Integrin a11, Integrin alpha-11

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, mouse

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

P61622

shipped in

dry ice

storage temp.

−20°C

Gene Information

mouse ... Itga11(319480)

General description

Integrin subunit α 11 (ITGA11) is expressed in stromal fibroblasts. Together with the integrin subunit β, it forms a receptor for collagen.

Immunogen

Peptide with sequence PTEEDLSHAPQRNH, from the internal region (near C-terminus) of the protein sequence according to NP_795896.4

Biochem/physiol Actions

Integrin subunit α 11 (ITGA11) may have a role in the organization of interstitial collagen matrices. It has been shown to be upregulated in non-small-cell lung carcinoma. Mice, which are deficient in ITGA11, exhibit signs of dwarfism and malnutrition.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

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Certificates of Analysis (COA)

Lot/Batch Number
0639P1
10639P1

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alpha11beta1 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal nonmuscle cells.
Tiger CF
Developmental Biology (2001)
Integrin a11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells
Chang-Qi Zhu
Proceedings of the National Academy of Sciences of the USA (2007)
a11?1 Integrin-Dependent Regulation of Periodontal Ligament Function in the Erupting Mouse Incisor
Svetlana N
Molecular and Cellular Biology (2007)

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