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Safety Information

RAB0429

Sigma-Aldrich

Human PAI-1 ELISA Kit

for serum, plasma, cell culture supernatant.

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32
Product RAB0429 is not currently sold in your country. Contact Technical Service

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 35 pg/mL
standard curve range: 0.102-25 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... SERPINE1(5054)

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manufacturer/tradename

Nalgene® 4110-0500

manufacturer/tradename

Nalgene® 4110-0250

manufacturer/tradename

Nalgene® 4110-1000

manufacturer/tradename

Nalgene® 4110-2000

material

straight neck transparent polycarbonate flask

material

beaded neck transparent polycarbonate flask

material

straight neck transparent polycarbonate flask

material

beaded neck translucent polycarbonate flask, transparent polycarbonate

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

feature

graduations 50 mL (Marked every 25mL at 400 - 500mL range), without cap

feature

cap: no, graduations 25 mL, without cap

feature

without cap

feature

graduations 200 mL, without cap

packaging

case of 4

packaging

case of 4

packaging

case of 2 ea

packaging

case of 2

General description

The Human PAI-1 (plasminogen activator inhibitor-1) ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PAI-1 in serum, plasma, cell culture supernatants. PAI-1 is 45kDa serine proteinase inhibitor.[1] It inhibits plasmogen activator and affects the fibrinolytic process, as a result of which it leads to thrombosis. Reduced fibrinolysis is observed in ischemic heart disease. While elevated PAI-1 levels are noticed in myocardial infarction.[2] PAI-1 is associated with various physiological processes including wound healing, sepsis, insulin resistance, obesity, atherosclerosis, tumor angiogenesis, bone remodeling, asthma, rheumatoid arthritis, glomerulonephritis and chronic stress.[1]

Immunogen

Recombinant Human PAI-I

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)
  • RABSTOP3ELISA Stop Solution (Item I)
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
  • RABWASH420X Wash Buffer (Item B)

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Regulatory Information

常规特殊物品

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    1110J0312
    1027J0312
    0426J0312
    0425J0312
    0428J0312

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    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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    Jessica Perugini et al.
    Scientific reports, 12(1), 8331-8331 (2022-05-19)
    To establish whether obesity involves activation of endogenous ciliary neurotrophic factor (CNTF) signalling, we evaluated its plasma levels in patients with obesity and correlated its values with the major clinical and haematological indices of obesity, insulin resistance and systemic inflammation.
    Pleiotropic functions of plasminogen activator inhibitor-1
    Lijnen, HR
    Journal of Thrombosis and Haemostasis, 3(1), 35-45 (2005)
    María Paniagua-Sancho et al.
    American journal of nephrology, 52(9), 714-724 (2021-09-15)
    Acute kidney injury (AKI) is a threatening, multiaetiological syndrome encompassing a variety of forms and damage patterns. AKI lacks sufficiently specific diagnostic tools to evaluate the distinct combination of pathophysiological events underlying each case, which limits personalized and optimized handling.
    Brain Edema XI: Proceedings of the 11th International Symposium, 277-277 (1999)
    Gui Yang et al.
    The Journal of allergy and clinical immunology, 133(6), 1702-1708 (2014-04-05)
    The functions of regulatory T (Treg) cells are important in immunity, and the regulatory mechanisms of Treg cell activities are not fully understood yet. We sought to investigate the role of insulin-like growth factor (IGF) 2 in the upregulation of

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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