PLA0140
Rabbit anti-Phospho KAP-1 (S824) Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
Sign Into View Organizational & Contract Pricing
All Photos(4)
Synonym(s):
E3 SUMO-protein ligase TRIM28, KAP-1, KAP1, KRAB [Kruppel-associated box domain]-associated protein 1, KRAB-associated protein 1, KRAB-interacting protein 1, KRIP-1, PPP1R157, RING finger protein 96, RNF96, TF1B, TIF1-beta, TIF1B, Tripartite motif-containing protein 28, nuclear corepressor KAP-1, protein phosphatase 1, regulatory subunit 157, transcriptional intermediary factor 1-beta
UNSPSC Code:
12352203
NACRES:
NA.43
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
grade
Powered by Bethyl Laboratories, Inc.
species reactivity
mouse, human
technique(s)
immunocytochemistry: 1:200-1:1,000
immunofluorescence: 1:200-1:1,000
immunohistochemistry: 1:2000-1:1,000
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000-1:10,000
accession no.
NP_005753.1
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
phosphorylation (pSer824)
Gene Information
human ... KIFAP3(22920)
Immunogen
Immunogen was a synthetic phosphorylated peptide, which represented a portion of human KRAB-Associated Protein 1 surrounding Serine 824 according to the numbering given in entry NP_005753.1 (GeneID 10155).
Physical form
Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide
Other Notes
KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
含少量动物源组分生物产品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Lei Shi et al.
Nature communications, 10(1), 2588-2588 (2019-06-15)
The brain is a genomic mosaic shaped by cellular responses to genome damage. Here, we manipulate somatic genome stability by conditional Knl1 deletion from embryonic mouse brain. KNL1 mutations cause microcephaly and KNL1 mediates the spindle assembly checkpoint, a safeguard
Kasumi Kawamura et al.
Journal of radiation research, 60(3), 281-288 (2019-03-07)
The nucleolus contains multiple copies of ribosomal (r)DNA, which indicate sites of frequent replication stress and suggest the existence of a mechanism to prevent replication stress-related rDNA instability and the possibility that such a mechanism contributes to the whole genomic
Matthias Pfeifer et al.
Journal of immunology (Baltimore, Md. : 1950), 202(12), 3423-3433 (2019-05-16)
Induction of programmed DNA damage and its recognition and repair are fundamental for B cell development. The ssDNA-binding protein SSB1 has been described in human cells as essential for the recognition and repair of DNA damage. To study its relevance
Bo-Ruei Chen et al.
The Journal of cell biology, 218(7), 2113-2123 (2019-05-28)
XRCC4-like factor (XLF) is a non-homologous end joining (NHEJ) DNA double strand break repair protein. However, XLF deficiency leads to phenotypes in mice and humans that are not necessarily consistent with an isolated defect in NHEJ. Here we show that
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service