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Merck
CN

P7908

N-(1-Pyrenyl)maleimide

Synonym(s):

1-(1-Pyrenyl)-1H-pyrrole-2,5-dione

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About This Item

Empirical Formula (Hill Notation):
C20H11NO2
CAS Number:
42189-56-0
Molecular Weight:
297.31
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24898892
EC Number:
255-702-1
Beilstein/REAXYS Number:
1542661
MDL number:
MFCD00049301
Form:
powder

Key Documents

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InChI key

YXKWRQLPBHVBRP-UHFFFAOYSA-N

InChI

1S/C20H11NO2/c22-17-10-11-18(23)21(17)16-9-7-14-5-4-12-2-1-3-13-6-8-15(16)20(14)19(12)13/h1-11H

SMILES string

O=C1C=CC(=O)N1c2ccc3ccc4cccc5ccc2c3c45

form

powder

mp

235-237 °C (lit.)

Quality Level

200

Related Categories

Application

Reactant used in synthesis of:
  • Oligodeoxynucleotide derivatives
  • Polymer conjugates of immunogenic peptides
  • Modified oligonucleotides for biosensing applications,

Reactant:
  • Involved in synthesis of thermally stable fluorescent maleimide/isobutene alternating copolymers
  • Used as derivitizing agent for determination of glutathione disulfide levels in biological samples

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
0000346227
0000346228
0000346228
0000346227
0000262200

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E A Johnson et al.
Biochemistry, 40(6), 1804-1811 (2001-05-01)
The intrinsic fluorescence of the catalytic portion of the chloroplast ATP synthase (CF1) is quenched when cysteine 322, the penultimate amino acid of the gamma subunit, is specifically labeled with pyrene maleimide (PM). The epsilon subunit of CF1 contains the
Joshua Ogony et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 843(1), 57-62 (2006-06-24)
2-Mercaptoethylamine (cysteamine) is an aminothiol compound used as a drug for the treatment of cystinosis, an autosomal recessive lysosomal storage disorder. Because of cysteamine's important role in clinical settings, its analysis by sensitive techniques has become pivotal. Unfortunately, the available
Jinhui Li et al.
Biochemistry, 43(2), 455-463 (2004-01-14)
Mutagenesis and cross-linking measurements have identified specific contact interactions between the cytosolic and the transmembrane sequences of phospholamban (PLB) and the Ca-ATPase, and in conjunction with the high-resolution structures of PLB and the Ca-ATPase, have been used to construct models
D Sahoo et al.
Biochemistry, 39(22), 6594-6601 (2000-06-01)
Manduca sexta apolipophorin III (apoLp-III), an 18-kDa, monomeric, insect hemolymph apolipoprotein, is comprised of five amphipathic alpha-helices arranged as a globular bundle in the lipid-free state. Upon lipid binding, it is postulated that the bundle opens, exposing a continuous hydrophobic
J M Warman et al.
Physics in medicine and biology, 56(5), 1487-1508 (2011-02-16)
We have produced an optically clear, close to water-equivalent gel that is radio-fluorogenic, i.e. fluoresces in UV light after exposure to high-energy radiation. Its potential as a 2D and 3D dosimetric medium is demonstrated by fixed fluorescent images of the
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感应染料

一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。

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