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P7527

Sigma-Aldrich

Prostaglandin E1

γ-irradiated, powder, BioXtra, suitable for cell culture

Synonym(s):

(11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid, Alprostadil, PGE1

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25 MG
¥565.00
100 MG
¥849.66
500 MG
¥3,714.20
1 G
¥6,253.45
5 G
¥23,728.37

¥565.00

Available to ship on2025年4月17日Details

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25 MG
¥565.00
100 MG
¥849.66
500 MG
¥3,714.20
1 G
¥6,253.45
5 G
¥23,728.37

About This Item

Empirical Formula (Hill Notation):
C20H34O5
CAS Number:
745-65-3
Molecular Weight:
354.48
Beilstein:
5294062
EC Number:
212-017-2
MDL number:
MFCD00077860
UNSPSC Code:
12352209
PubChem Substance ID:
24898855
NACRES:
NA.77
biological source:
synthetic (organic)
form:
powder

¥565.00

Available to ship on2025年4月17日Details

Request a Bulk Order

biological source

synthetic (organic)

Quality Level

200

sterility

γ-irradiated

product line

BioXtra

Assay

≥60% (HPLC)

form

powder

concentration

≥60% (HPLC)

technique(s)

cell culture | mammalian: suitable

solubility

ethanol: 1 mg/mL

storage temp.

−20°C

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GE10600000GE10600012GE10600010
Amersham™ Protran® Western blotting membranes, nitrocellulose pore size 0.45 μm, roll W × L 300 mm × 4 m, pkg of 1 ea

GE10600002

Amersham™ Protran® Western blotting membranes, nitrocellulose

Amersham™ Protran® Western blotting membranes, nitrocellulose pore size 0.1 μm, roll W × L 300 mm × 4 m, pkg of 1 ea

GE10600000

Amersham™ Protran® Western blotting membranes, nitrocellulose

Amersham™ Protran® Western blotting membranes, nitrocellulose pore size 0.45 μm, roll W × L 150 mm × 4 m, pkg of 1 ea

GE10600012

Amersham™ Protran® Western blotting membranes, nitrocellulose

Amersham™ Protran® Western blotting membranes, nitrocellulose pore size 0.1 μm, roll W × L 150 mm × 4 m, pkg of 1 ea

GE10600010

Amersham™ Protran® Western blotting membranes, nitrocellulose

packaging

pkg of 1 ea

packaging

pkg of 1 ea

packaging

pkg of 1 ea

packaging

pkg of 1 ea

manufacturer/tradename

Cytiva 10600002

manufacturer/tradename

Cytiva 10600000

manufacturer/tradename

Cytiva 10600012

manufacturer/tradename

Cytiva 10600010

pore size

0.45 μm pore size

pore size

0.1 μm pore size

pore size

0.45 μm pore size

pore size

0.1 μm pore size

Application

For use in cell culture applications for the study of prostaglandin regulated cell signaling and gene regulation.
Prostaglandin E1 has been used in maintaining mice proximal tubule,[1] and NRK-52E, a rat renal epithelial cell line.[2]

Biochem/physiol Actions

Prostaglandins mediate vasodilation and vasoconstriction, the E series of prostaglandin is a highly effective vasodilator. It is known to efficiently cause erythema. Prostaglandin E1 is considered as a potent pyretic factor, and acts through cerebral ventricles.[3] Prostaglandin E1 is useful to prolong cardiovascular function in new born suffering from ductus-dependant congenital heart disease until surgery.[4]

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000314222
    0000314222
    SLCM7287
    SLCL8094
    SLCF2442

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    The Prostaglandins (2013)
    Long-term prostaglandin E1 infusion for newborns with critical congenital heart disease
    Aykanat A, et al.
    Pediatric Cardiology, 37(1), 131-134 (2016)
    Naturally produced crystals obtained from kidney stones are less injurious to renal tubular epithelial cells than synthetic crystals
    Escobar C, et al.
    BJU International, 100(4), 891-897 (2007)
    Signe E Cremer et al.
    PloS one, 14(11), e0224891-e0224891 (2019-11-14)
    Domestic dogs share the same environment as humans, and they represent a valuable animal model to study naturally-occurring human disease. Platelet proteomics holds promise for the discovery of biomarkers that capture the contribution of platelets to the pathophysiology of many
    Mark S Szczypka et al.
    Stem cells (Dayton, Ohio), 23(1), 44-54 (2004-12-31)
    Results obtained in recent experiments suggest that bone marrow-derived cells (BMDCs) engraft into tissues and differentiate into various somatic cell types. However, it is unclear whether injury is required for the phenomenon to occur at appreciable frequencies. In this study
    View All Related Papers

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