Skip to Content
Merck
CN

O9637

Oxaprozin

solid

Synonym(s):

4,5-Diphenyl-2-oxazolepropanoic acid, Daypro

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C18H15NO3
CAS Number:
21256-18-8
Molecular Weight:
293.32
NACRES:
NA.77
PubChem Substance ID:
24278617
UNSPSC Code:
12352200
EC Number:
244-296-1
MDL number:
MFCD00215977

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)

InChI key

OFPXSFXSNFPTHF-UHFFFAOYSA-N

SMILES string

OC(=O)CCc1nc(-c2ccccc2)c(o1)-c3ccccc3

form

solid

Quality Level

200

Gene Information

human ... PTGIR(5739), PTGS1(5742), PTGS2(5743)

Looking for similar products? Visit Product Comparison Guide

General description

Oxaprozin is a non-steroidal anti-inflammatory drug prescribed for rheumatoid arthritis (RA) and osteoarthritis (OA). Oxaprozin binds to albumin. It inhibits arachidonic acid pathway. Oxaprozin has anti-inflammatory property and is an effective inhibitor of cyclooxygenase enzymes, COX-1 and COX-2.

Application

Anti-inflammatory

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000502174
0000502174
0000497700
0000497700
101K1304

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Shao-Fa Sun et al.
International journal of biological macromolecules, 39(4-5), 197-200 (2006-07-11)
The interaction between Oxaprozin-E and bovine serum albumin (BSA) was studied by spectroscopic methods including fluorescence and UV-vis absorption spectroscopy. The quenching mechanism of fluorescence of BSA by Oxaprozin-E was discussed to be a dynamic quenching procedure. The number of
Recent pharmacodynamic and pharmacokinetic findings on oxaprozin
Rainsford KD, et al.
Inflammopharmacology, 10(3), 185-239 (2002)
Isa M Kara et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 68(5), 1018-1024 (2010-03-09)
In this study, oxaprozin, a long-acting nonsteroidal anti-inflammatory drug, and naproxen sodium were compared in terms of their effects on edema, pain, and trismus after surgery for impacted mandibular third molars. Thirty healthy patients with bilaterally impacted mandibular third molars
Allen Brinker et al.
Drugs & aging, 21(7), 479-484 (2004-05-11)
Data on file with the US FDA, and other published studies, suggest that the selective cyclo-oxygenase (COX)-2 inhibitor NSAID rofecoxib has a greater hypertensive adverse effect than other NSAIDs, including celecoxib. In this study we describe a pharmacoepidemiologic analysis of
Bojan D J Božić et al.
Chemical & pharmaceutical bulletin, 60(7), 865-869 (2012-07-14)
A series of novel Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes with oxaprozin (Hoxa), a non-steroidal anti-inflammatory drug, has been synthesized. The drug and complexes have been characterized by elemental and thermogravimetric (TG) analysis, Fourier transform (FT)-IR, 1H-NMR, 13C-NMR, UV-Vis
View All Related Papers

Articles

Bioactive Molecules for Immunology Research

Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service