N6007
1-Nitrosopiperidine
Synonym(s):
NPIP
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C5H10N2O
CAS Number:
Molecular Weight:
114.15
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
202-886-6
MDL number:
SMILES string
O=NN1CCCCC1
density
1.06 g/mL (lit.)
storage temp.
2-8°C
Biochem/physiol Actions
Carcinogen that induces benign and malignant tumors of the respiratory tract, stomach and esophagus in rodents; potent nasal carcinogen in rats.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Samuel González-Mancebo et al.
Mutation research, 558(1-2), 45-51 (2004-03-24)
The genotoxicity of nitrosopiperidine and six alkyl derivatives was studied by use of the Ames tester strains TA100 and TA1535 in the pre-incubation method. Among the compounds investigated, those exhibiting genotoxic activity under the experimental conditions employed were only genotoxic
Almudena García et al.
Cell biology international, 33(12), 1280-1286 (2009-09-15)
The human hepatoma cell line (HepG2) exhibited a dose and time-dependent apoptotic response following treatment with N-Nitrosopiperidine (NPIP) and N-Nitrosodibutylamine (NDBA), two recognized human carcinogens. Our results showed a significant apoptotic cell death (95%) after 24h treatment with NDBA (3.5
Y Yamashita et al.
Mutation research, 348(4), 163-168 (1995-12-01)
N-Nitrosodialkylamines are promutagens and proclastogens, requiring metabolic activation for their actions. Previously, we showed that direct-acting bacterial mutagens can be formed from N-nitrosodialkylamines on exposure to near-UV. We have now found that N-nitrosodialkylamines with near-UV irradiation are clastogenic to Chinese
P Levallois et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 38(11), 1013-1019 (2000-10-19)
Urinary excretion of volatile nitrosamines was assessed in 59 non-smokers living in a rural county of Québec, Canada. Water and food intakes were measured by means of a 24-hour recall. Nitrates were analyzed in the tap water of all participants
Dennie G A J Hebels et al.
Toxicology letters, 207(3), 232-241 (2011-09-29)
N-nitroso compounds (NOCs) may represent a carcinogenic risk to humans following endogenous colonic nitrosation processes. We used the colon adenocarcinoma cell line Caco-2 to investigate transcriptomic changes at three time points (1, 6, 24 h) following exposure to genotoxic concentrations
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service