All Photos(1)
Synonym(s):
NPIP
Empirical Formula (Hill Notation):
C5H10N2O
CAS Number:
Molecular Weight:
114.15
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Recommended Products
density
1.06 g/mL (lit.)
storage temp.
2-8°C
SMILES string
O=NN1CCCCC1
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Biochem/physiol Actions
Carcinogen that induces benign and malignant tumors of the respiratory tract, stomach and esophagus in rodents; potent nasal carcinogen in rats.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Samuel González-Mancebo et al.
Mutation research, 558(1-2), 45-51 (2004-03-24)
The genotoxicity of nitrosopiperidine and six alkyl derivatives was studied by use of the Ames tester strains TA100 and TA1535 in the pre-incubation method. Among the compounds investigated, those exhibiting genotoxic activity under the experimental conditions employed were only genotoxic
Dennie G A J Hebels et al.
Toxicology letters, 207(3), 232-241 (2011-09-29)
N-nitroso compounds (NOCs) may represent a carcinogenic risk to humans following endogenous colonic nitrosation processes. We used the colon adenocarcinoma cell line Caco-2 to investigate transcriptomic changes at three time points (1, 6, 24 h) following exposure to genotoxic concentrations
P Levallois et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 38(11), 1013-1019 (2000-10-19)
Urinary excretion of volatile nitrosamines was assessed in 59 non-smokers living in a rural county of Québec, Canada. Water and food intakes were measured by means of a 24-hour recall. Nitrates were analyzed in the tap water of all participants
Y Yamashita et al.
Mutation research, 348(4), 163-168 (1995-12-01)
N-Nitrosodialkylamines are promutagens and proclastogens, requiring metabolic activation for their actions. Previously, we showed that direct-acting bacterial mutagens can be formed from N-nitrosodialkylamines on exposure to near-UV. We have now found that N-nitrosodialkylamines with near-UV irradiation are clastogenic to Chinese
I T Vermeer et al.
Mutation research, 428(1-2), 353-361 (1999-10-13)
Many constituents present in the human diet may inhibit endogenous formation of N-nitroso compounds (NOC). Studies with human volunteers showed inhibiting effects of intake of ascorbic acid and green tea consumption on nitrosation using the N-nitrosoproline test. The aim of
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