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MSQC22

Sigma-Aldrich

SILu™Lite SigmaMAb Trastuzumab Monoclonal Antibody

recombinant, expressed in CHO cells

Synonym(s):

Mass spectrometry standard, Tratuzumab

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

recombinant

expressed in CHO cells

Assay

≥90% (SDS-PAGE)

form

solid

suitability

suitable for mass spectrometry

shipped in

wet ice

storage temp.

−20°C

Related Categories

General description

SigmaMAb Trastuzumab (MSQC22) is designed to be a standard for the analysis of Trastuzumab monoclonal antibodies using mass spectrometry. An isotopically labeled version is available as SILu™Mab Trastuzumab (MSQC23).


SigmaMAb Trastuzumab comprises 500 µg of lyophilized antibody from the phosphate-buffered saline solution.

Sequence

SigmaMab Trastuzumab Heavy Chain:
EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG

SigmaMab Trastuzumab Light Chain:
DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Other Notes

SigmaMAb Trastuzumab is for R&D use only. Not for drugs, households, or other uses.

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

WGK

WGK 3

Regulatory Information

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Certificates of Analysis (COA)

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Articles

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Method development for titer determination of three different monoclonal antibodies - cetuximab, trastuzumab, and universal antibody standard using a Chromolith® WP 300 Protein A column.

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