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L2125

Sigma-Aldrich

L-Leucine tert-butyl ester hydrochloride

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Linear Formula:
(CH3)2CHCH2CH(NH2)COOC(CH3)3 · HCl
CAS Number:
Molecular Weight:
223.74
Beilstein:
3697141
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.26

Assay

≥98% (TLC)

form

powder

color

white

storage temp.

−20°C

SMILES string

Cl.CC(C)C[C@H](N)C(=O)OC(C)(C)C

InChI

1S/C10H21NO2.ClH/c1-7(2)6-8(11)9(12)13-10(3,4)5;/h7-8H,6,11H2,1-5H3;1H/t8-;/m0./s1

InChI key

RFUWRXIYTQGFGA-QRPNPIFTSA-N

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WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Naoatsu Shibata et al.
The Journal of organic chemistry, 75(16), 5707-5715 (2010-08-14)
Reversal of enantioselectivity in a Cu-catalyzed asymmetric conjugate addition reaction of dialkylzinc to cyclic enone with use of the same chiral ligand was successfully achieved. The reaction of 2-cyclohexen-1-one (30) with Et(2)Zn catalyzed by Cu(OTf)(2) in the presence of an
Cuie Wang et al.
Langmuir : the ACS journal of surfaces and colloids, 27(19), 12058-12068 (2011-08-23)
Infrared spectroscopy was applied to investigate the well-known EDC/NHS (N-ethyl-N'-(3-(dimethylamino)propyl)carbodiimide/N-hydroxysuccinimide) activation details of poly(acrylic acid) (PAA) and poly(methacrylic acid) (PMAA) brushes grafted on porous silicon. Succinimidyl ester (NHS-ester) is generally believed to be the dominant intermediate product, conveniently used to
Jan Pícha et al.
Amino acids, 39(5), 1265-1280 (2010-03-30)
In the present study, we describe in detail the synthesis of a relatively rare class of phosphorus compounds, α-carboxyphosphinopeptides. We prepared several norleucine-derived α-carboxyphosphinic pseudopeptides of the general formula Nle-Ψ[PO(OH)]-Gly. These compounds could have important applications as transition state-mimicking inhibitors
David Schachter et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(11), G938-G946 (2014-04-05)
The leucine-to-glutamate (Leu→Glu) pathway, which metabolizes the carbon atoms of l-leucine to form l-glutamate, was studied by incubation of rat tissue segments with l-[U-(14)C]leucine and estimation of the [(14)C]glutamate formed. Metabolism of the leucine carbon chain occurs in most rat

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