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I6635

Sigma-Aldrich

Monoclonal Anti-Secretory Component (IgA) antibody produced in mouse

clone GA-1, ascites fluid

Synonym(s):

IgA Antibody, Secretory Component Antibody

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0.2 ML
CN¥1,711.63
0.5 ML
CN¥11,410.86

CN¥1,711.63

List PriceCN¥5,705.44Save 70%

Available to ship onApril 25, 2025Details

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0.2 ML
CN¥1,711.63
0.5 ML
CN¥11,410.86

About This Item

MDL number:
MFCD00162469
UNSPSC Code:
12352203
NACRES:
NA.46

CN¥1,711.63

List PriceCN¥5,705.44Save 70%

Available to ship onApril 25, 2025Details

Request a Bulk Order

biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

GA-1, monoclonal

contains

15 mM sodium azide

species reactivity

human

technique(s)

indirect ELISA: 1:10,000

isotype

IgG1

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This Item
SAB4200787I6260I6135
Monoclonal Anti-Secretory Component (IgA) antibody produced in mouse clone GA-1, ascites fluid

I6635

Monoclonal Anti-Secretory Component (IgA) antibody produced in mouse

Anti-Secretory Component (IgA) antibody, Mouse monoclonal clone GA-1, purified from hybridoma cell culture

SAB4200787

Anti-Secretory Component (IgA) antibody, Mouse monoclonal

Monoclonal Anti-Human IgG (Fc specific) antibody produced in mouse clone GG-7, ascites fluid

I6260

Monoclonal Anti-Human IgG (Fc specific) antibody produced in mouse

Monoclonal Anti-Human IgG (Fab specific) antibody produced in mouse clone GG-6, ascites fluid

I6135

Monoclonal Anti-Human IgG (Fab specific) antibody produced in mouse

antibody form

ascites fluid

antibody form

purified from hybridoma cell culture

antibody form

ascites fluid

antibody form

ascites fluid

species reactivity

human

species reactivity

human

species reactivity

-

species reactivity

-

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

conjugate

unconjugated

clone

GA-1, monoclonal

clone

GA-1, monoclonal

clone

GG-7, monoclonal

clone

GG-6, monoclonal

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

technique(s)

indirect ELISA: 1:10,000

technique(s)

indirect ELISA: 0.06-0.12 μg/mL using 5 μg/ml secretory human IgA for coating.

technique(s)

indirect ELISA: 1:40,000

technique(s)

indirect ELISA: 1:20,000

General description

The secretory component is a single chain glycoprotein that may occur freely or as component of the secretory immunoglobulin A (SIgA). IgA regulates the physiological balance between commensal intestinal bacteria and the defenses of the host immune system. It is the highest generated antibody isotype. IgAs are mainly secreted in the intestinal mucosa and prevent the commensal microorganisms from invading the intestines
Monoclonal Anti-Secretory Component (IgA) antibody is specific for secretory human IgA and the free secretory component. The antibody does not bind to human IgG, IgM and IgE.

Immunogen

Secretory component purified from human colostrum

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper)
Monoclonal Anti-Secretory Component (IgA) antibody has been used in immunohistochemistry analysis and serological assays.
Monoclonal Anti-Secretory Component (IgA) antibody is suitable for use in EIA and western blot. The product may also be used for indirect ELISA (1:10,000).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000145827
    0000141281
    0000137689
    0000130359

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    Alpha Fardah Athiyyah et al.
    Iranian journal of microbiology, 11(4), 300-304 (2019-11-14)
    Probiotics and prebiotics are known to regulate immune responses. A synbiotic is a product that combines probiotics and prebiotics in a single dosage form. In this study, we attempt to present the effects of a multispecies synbiotic on intestinal mucosa
    C G Engeland et al.
    Brain, behavior, and immunity, 52, 11-17 (2015-09-01)
    Stress-induced impairments of mucosal immunity may increase susceptibility to infectious diseases. The present study investigated the association of perceived stress, depressive symptoms, and loneliness with salivary levels of secretory immunoglobulin A (S-IgA), the subclasses S-IgA1, S-IgA2, and their transporter molecule
    Muna Sapkota et al.
    Alcoholism, clinical and experimental research, 41(12), 2093-2099 (2017-09-25)
    Malondialdehyde (MDA) and acetaldehyde (AA) exist following ethanol metabolism and tobacco pyrolysis. As such, lungs of individuals with alcohol use disorders (AUDs) are a target for the effects of combined alcohol and cigarette smoke metabolites. MDA and AA form a
    B Simell et al.
    The Journal of infectious diseases, 183(6), 887-896 (2001-03-10)
    Local antibodies probably contribute to defense against Streptococcus pneumoniae. This study examined whether pneumococcal carriage and acute otitis media (AOM) induce mucosal antibodies to potential vaccine candidates pneumococcal surface adhesin A (PsaA), pneumolysin (Ply), and pneumococcal surface protein A (PspA).
    Min Zhao et al.
    Experimental and therapeutic medicine, 14(5), 4033-4040 (2017-10-28)
    Redox imbalance is established in various human diseases. Treatment of intestinal epithelial cells with hyperoxia for a prolonged period of time may cause serious effects on redox balance. Secretory component (SC) protein is secreted by intestinal epithelial cells, and has
    View All Related Papers

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