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Key Documents

Safety Information

G9887

Sigma-Aldrich

γ-Globulins from sheep

≥99% (agarose gel electrophoresis)

Synonym(s):

Gamma globulin

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About This Item

CAS Number:
9007-83-4
EC Number:
232-706-1
MDL number:
MFCD01114257
UNSPSC Code:
12352202
NACRES:
NA.61
Pricing and availability is not currently available.

biological source

sheep

Quality Level

200

Assay

≥99% (agarose gel electrophoresis)

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

≤4% NaCl

storage temp.

−20°C

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γ-Globulins 来源于绵羊 ≥99% (agarose gel electrophoresis)

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γ-球蛋白 来源于小鼠

γ-球蛋白 来源于人类血液 ≥99% (electrophoresis)

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γ-球蛋白 来源于人类血液

白蛋白 来源于绵羊血清 lyophilized powder

A3264

白蛋白 来源于绵羊血清

biological source

sheep

biological source

mouse

biological source

human blood

biological source

sheep

technique(s)

cell culture | mammalian: suitable

technique(s)

ELISA: suitable

technique(s)

protein quantification: suitable

technique(s)

hybridization: suitable, microbiological culture: suitable, protein quantification: suitable

form

powder

form

powder

form

powder

form

lyophilized powder

impurities

≤4% NaCl

impurities

≤4% NaCl

impurities

HIV, HCV and HBsAg, source material tested negative, ≤4% NaCl

impurities

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

General description

γ-Globulin molecules is made up of four polypeptide chains, of which two have molecular weights of about 50,000 and two of about 20,000. These chains are cross-linked by disulfide bonds.[1]

Application

γ-Globulins from sheep were used to study the influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI.[2] It was used in a study to test the interstitial transport of rabbit and sheep antibodies in normal and neoplastic tissues.[3] It was also used in a study to test the enhanced progesterone and testosterone secretion, and depressed estradiol secretion in vitro from small white follicle cells of incubating turkey hens.[4]

Preparation Note

Prepared from Cohn Fraction II, III

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000294880
    0000293301
    0000294880
    0000293301
    032H9323

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    T E Porter et al.
    General and comparative endocrinology, 74(3), 400-405 (1989-06-01)
    This study was conducted to determine if lower steroid secretion by the small white follicles in incubating turkey hens contributes to lower circulating steroid concentrations during this time. Turkey hens were grouped as either laying or incubating. Serum samples and
    M A Clauss et al.
    Cancer research, 50(12), 3487-3492 (1990-06-15)
    Interstitial transport of fluorescein isothiocyanate-conjugated nonspecific polyclonal rabbit and sheep IgG was studied in normal (mature granulation) and neoplastic (VX2 carcinoma) tissues grown in a rabbit ear chamber. The interstitial concentration gradients after i.v. injection were analyzed to yield effective
    Thomas J F Nieland et al.
    Journal of lipid research, 48(8), 1832-1845 (2007-05-30)
    Treatment of atherosclerotic disease often focuses on reducing plasma LDL-cholesterol or increasing plasma HDL-cholesterol. We examined in vitro the effects on HDL receptor [scavenger receptor class B type I (SR-BI)] activity of three classes of clinical and experimental plasma HDL-cholesterol-elevating
    [Postoperative thrombosis prevention using low-dose heparin].
    A E Schaer et al.
    Archiv fur Gynakologie, 219(1-4), 545-545 (1975-11-18)

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