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Key Documents

Safety Information

G9287

Sigma-Aldrich

Globotriose

Synonym(s):

α-D-Gal-(1→4)-β-D-Gal-(1→4)-D-Glc, 4-O-(4-O-α-D-Galactopyranosyl-β-D-galactopyranosyl)-D-glucopyranose

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About This Item

Empirical Formula (Hill Notation):
C18H32O16
CAS Number:
Molecular Weight:
504.44
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:

Assay

≥95% (HPLC)

Quality Level

form

powder

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@H](O[C@@H]2[C@H](O)[C@@H](O)[C@@H](O[C@@H]2CO)O[C@H]3[C@H](O)[C@@H](O)C(O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C18H32O16/c19-1-4-7(22)8(23)12(27)17(31-4)34-15-6(3-21)32-18(13(28)10(15)25)33-14-5(2-20)30-16(29)11(26)9(14)24/h4-29H,1-3H2/t4-,5-,6-,7+,8+,9-,10-,11-,12-,13-,14-,15+,16?,17-,18+/m1/s1

InChI key

FYGDTMLNYKFZSV-ANKSBSNASA-N

Other Notes

To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

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Romina J Fernández-Brando et al.
PloS one, 6(4), e19136-e19136 (2011-05-12)
Shiga toxin (Stx)-producing Escherichia coli (STEC) infection is associated with a broad spectrum of clinical manifestations that include diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome (HUS). Systemic Stx toxemia is considered to be central to the genesis of HUS. Distinct
Jianbo Zhang et al.
Carbohydrate research, 337(11), 969-976 (2002-06-01)
A truncated alpha-(1-->4)-galactosyltransferase (LgtC) gene from Neisseria meningitidis was cloned. The recombinant glycosyltransferase was expressed in Escherichia coli BL21 (DE3) strain with high specific activity (5 units/mg protein). Its acceptor specificity was carefully characterized. Then the purified enzyme was utilized
Yuh-Yih Chien et al.
Chembiochem : a European journal of chemical biology, 9(7), 1100-1109 (2008-04-10)
Compared to monovalent carbohydrates, multivalent carbohydrate ligands exhibit significantly enhanced binding affinities to their interacting proteins. Here, we report globotriose (P(k) ligand)-functionalized gold nanoparticle (AuNP) probes for the investigation of multivalent interactions with the B(5) subunit of Shiga-like toxin I
Koji Matsuoka et al.
Biomacromolecules, 7(8), 2274-2283 (2006-08-15)
As an application of a one-pot reaction involving Birch reduction and subsequent S(N)2 reaction in liquid ammonia, synthetic assembly of trisaccharidic moieties of globotriaosyl ceramide onto carbosilane dendrimers was accomplished using tris(3-bromopropyl)phenylsilane and tris[tris(3-bromopropyl)silylpropyl]phenylsilane as the core scaffolds. The common
P I Kitov et al.
Carbohydrate research, 307(3-4), 361-369 (1998-07-24)
The Pk trisaccharide and the central disaccharide element of asialo GM1 activated as their trichloroacetimidates were each used to glycosylate 16-(p-toluensulfonyloxy) hexadecanol 1. Displacement of the tosyl group by thiocyanate followed by sodium borohydride reduction and saponification afforded oligosaccharide 16-mercaptohexadecanyl

Articles

O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

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