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Merck
CN

G9287

Globotriose

Synonym(s):

α-D-Gal-(1→4)-β-D-Gal-(1→4)-D-Glc, 4-O-(4-O-α-D-Galactopyranosyl-β-D-galactopyranosyl)-D-glucopyranose

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About This Item

Empirical Formula (Hill Notation):
C18H32O16
CAS Number:
66580-68-5
Molecular Weight:
504.44
UNSPSC Code:
12352201
PubChem Substance ID:
329799986
MDL number:
MFCD01076415

Key Documents

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InChI

1S/C18H32O16/c19-1-4-7(22)8(23)12(27)17(31-4)34-15-6(3-21)32-18(13(28)10(15)25)33-14-5(2-20)30-16(29)11(26)9(14)24/h4-29H,1-3H2/t4-,5-,6-,7+,8+,9-,10-,11-,12-,13-,14-,15+,16?,17-,18+/m1/s1

SMILES string

OC[C@H]1O[C@H](O[C@@H]2[C@H](O)[C@@H](O)[C@@H](O[C@@H]2CO)O[C@H]3[C@H](O)[C@@H](O)C(O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@H]1O

InChI key

FYGDTMLNYKFZSV-ANKSBSNASA-N

assay

≥95% (HPLC)

form

powder

storage temp.

2-8°C

Quality Level

200

Other Notes

To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
SLBT5524
SLBL3967V
SLBK6410V
SLBF1813V
SLBC9581V

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Hirofumi Dohi et al.
Carbohydrate research, 337(11), 983-989 (2002-06-01)
New thioglycosyl donors (o-methoxycarbonylphenyl 2,3,4,6-tetra-O-benzyl-1-thio-beta-D-galactopyranoside and its 6-O-acetyl analogue) were designed and used for the synthesis of glycoconjugate polymers carrying Gb(3) [Gal(alpha1-->4)Gal(beta1-->4)Glc] and isoGb(3) [Gal(alpha1-->3)Gal(beta1-->4)Glc] clusters as side chains. These donors scarcely evolved the unpleasant odor of thiophenols and showed
James L Leach et al.
Antimicrobial agents and chemotherapy, 49(9), 3842-3846 (2005-08-30)
Epithelial cells lining the urinary tract are rich in globo series glycolipids, structurally defined by a Galalpha1,4Gal motif in the oligosaccharide moiety of this glycolipid family. This Galalpha1,4Gal motif is the attachment target for the P-fimbrial adhesin of uropathogenic Escherichia
H C Hansen et al.
Carbohydrate research, 307(3-4), 243-251 (1998-07-24)
Derivatives of galabiose (alpha-D-Galp-(1-->4)-D-Galp) and globotriose (a-D-Galp-(1-->4)-beta-D-Galp-(1-->4)-D-Glcp) were coupled to various 1,2- and 1,3-dihydroxymethyl- and dimercapto-methylbenzenes to give the corresponding divalent glycosides, potentially useful as inhibitors of bacterial adhesion.
Alipio Pinto et al.
PloS one, 8(7), e70020-e70020 (2013-07-31)
Shiga toxin 2 (Stx2)-producing Escherichia coli (STEC) causes hemorrhagic colitis and hemolytic uremic syndrome (HUS) that can lead to fatal encephalopathies. Neurological abnormalities may occur before or after the onset of systemic pathological symptoms and motor disorders are frequently observed
H C Hansen et al.
Carbohydrate research, 322(3-4), 166-180 (2000-01-19)
Six aminodeoxy 2-(trimethylsilyl)ethyl (Me3SiEt) glycoside analogues of galabiose (4'- and 6'-aminodeoxy) and globotriose (6"-, 4"-, 2"-, and 6'-aminodeoxy) were synthesized by glycosylation of protected Me3SiEt galactoside and lactoside acceptors with azido-substituted monosaccharide donors, followed by reduction of the azido groups
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Articles

Review of O-Linked Glycoproteins

O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

O-连接糖蛋白回顾

O-连接糖蛋白通常是分子量>200kDa的大蛋白。糖基化通常发生在高密度簇上，并可占总量的50-80%。

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