G6503
4-Guanidinobutyric acid
≥98%, for peptide synthesis
Synonym(s):
γ-Guanidinobutyric acid
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About This Item
Linear Formula:
NH=C(NH2)NHCH2CH2CH2COOH
CAS Number:
Molecular Weight:
145.16
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
207-331-1
MDL number:
Beilstein/REAXYS Number:
1766447
Product Name
4-Guanidinobutyric acid, ≥98%
InChI key
TUHVEAJXIMEOSA-UHFFFAOYSA-N
InChI
1S/C5H11N3O2/c6-5(7)8-3-1-2-4(9)10/h1-3H2,(H,9,10)(H4,6,7,8)
SMILES string
NC(=N)NCCCC(O)=O
assay
≥98%
form
powder or chunks
technique(s)
drug transporter assay: suitable
color
white
mp
280-282 °C
storage temp.
2-8°C
Quality Level
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Application
Gamma-Guanidinobutyric acid (4-GBA) is used to study intestinal transport by the human proton-coupled amino acid transporter(s) (hPAT1). 4-GBA is used with other model compounds such as 1,6-diaminohexane, 1,6-diguanidinohexane, and 1,6-di(cyanoguanidino)hexane to study the biodegradability of the biocide polyhexamethylene biguanide (PHMB).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Zhipan Zhang et al.
The journal of physical chemistry. B, 109(46), 21818-21824 (2006-07-21)
Dye-sensitized solar cells based on nanocrystalline TiO(2) have been fabricated with an amphiphilic ruthenium sensitizer [Ru (4,4'-dicarboxylic acid-2,2'-bipyridine) (4,4'-bis(p-hexyloxystyryl)-2,2'-bipyridine)(NCS)(2)], coded as K-19, and 4-guanidinobutyric acid (GBA) as coadsorbent. The cells showed a approximately 50 mV increase in open-circuit voltage and
Guanidino compounds in hyperargininemia.
B Marescau et al.
Advances in experimental medicine and biology, 153, 427-434 (1982-01-01)
S Shindo et al.
Research communications in chemical pathology and pharmacology, 54(1), 73-85 (1986-10-01)
Arginine levels diminished markedly in the plasma during starvation, suggesting that plasma arginine level principally depends on food intake. Organ arginine levels were relatively stable except for an extraordinary increase in the pancreas at 96 h. Guanidinoacetic acid decreased dramatically
M Al Banchaabouchi et al.
Metabolism: clinical and experimental, 47(3), 355-361 (1998-03-21)
Renal failure is characterized by the retention of nitrogenous metabolites such as urea, creatinine (CTN) and other guanidino compounds (GCs), uric acid, and hippuric acid, which could be related to the clinical syndrome associated with renal insufficiency. A model of
Metabolism of arginine in invertebrates: relation to urea cycle and to other guanidine derivatives.
Y Robin
Advances in experimental medicine and biology, 153, 407-417 (1982-01-01)
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