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Key Documents

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Safety Information

G1272

Sigma-Aldrich

Gentamicin

liquid, non-animal origin, suitable for cell culture, BioReagent

Synonym(s):

Garamycin, Gentiomycin C

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CN¥6,110.23

CN¥6,110.23

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About This Item

CAS Number:
1405-41-0
EC Number:
215-778-9
MDL number:
MFCD00270181
UNSPSC Code:
12352207
eCl@ss:
42020823
PubChem Substance ID:
329799834
NACRES:
NA.76

CN¥6,110.23

Please contact Customer Service for Availability
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Product Name

Gentamicin solution, 10 mg/mL in deionized water, liquid, 0.1 μm filtered, BioReagent, suitable for cell culture

biological source

microbial

Quality Level

300

sterility

0.1 μm filtered

product line

BioReagent

form

liquid

potency

10-12 mg per mL

concentration

10 mg/mL in deionized water

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

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This Item
28476U28466U28467U
SLB®-5ms Capillary GC Column L × I.D. 20 m × 0.18 mm, df 0.18 μm

28564U

SLB®-5ms Capillary GC Column

SLB®-5ms Capillary GC Column L × I.D. 30 m × 0.25 mm, df 1.00 μm

28476U

SLB®-5ms Capillary GC Column

SLB®-5ms Capillary GC Column L × I.D. 15 m × 0.10 mm, df 0.10 μm

28466U

SLB®-5ms Capillary GC Column

SLB®-5ms Capillary GC Column L × I.D. 30 m × 0.25 mm, df 0.10 μm

28467U

SLB®-5ms Capillary GC Column

df

0.18 μm

df

1.00 μm

df

0.10 μm

df

0.10 μm

parameter

-60-340 °C temperature (isothermal), -60-360 °C temperature (programmed)

parameter

-60-340 °C temperature (isothermal), -60-360 °C temperature (programmed)

parameter

-60-340 °C temperature (isothermal), -60-360 °C temperature (programmed)

parameter

-60-340 °C temperature (isothermal), -60-360 °C temperature (programmed)

material

fused silica

material

fused silica

material

fused silica

material

fused silica

technique(s)

GC/MS: suitable, gas chromatography (GC): suitable (fast GC)

technique(s)

GC/MS: suitable, gas chromatography (GC): suitable

technique(s)

GC/MS: suitable, gas chromatography (GC): suitable (fast GC)

technique(s)

GC/MS: suitable, gas chromatography (GC): suitable

application(s)

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
industrial hygiene
life science and biopharma
personal care
petroleum
pharmaceutical (small molecule)

application(s)

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
industrial hygiene
life science and biopharma
personal care
petroleum
pharmaceutical (small molecule)

application(s)

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
industrial hygiene
life science and biopharma
personal care
petroleum
pharmaceutical (small molecule)

application(s)

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
industrial hygiene
life science and biopharma
personal care
petroleum
pharmaceutical (small molecule)

General description

Chemical structure: aminoglycoside

Application

Gentamicin sulfate is a broad-spectrum antibiotic used as a selection agent (gentamicin-resistance gene) in molecular biology and cell culture applications. This product is formulated to contain 10 mg/mL Gentamicin in deionized water and is recommended for use in eukaryotic cell culture at a volume of 1 milliliter per liter.

Biochem/physiol Actions

Mode of Action: Gentamicin inhibits protein synthesis by binding to the 30S subunit of the ribosome.

Antimicrobial spectrum: Includes Gram-negative and Gram-positive bacteria, including strains resistant to tetracycline, chloramphenicol, kanamycin and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus and Streptococcus.

Components

Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base.

Caution

The product is stable at 37° for 5 days and is stored at 2-8°C.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000406660
    0000406661
    0000406659
    0000406660
    0000406659

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    Cristina Furlan et al.
    Nature communications, 10(1), 1525-1525 (2019-04-06)
    Essentially all cellular processes are orchestrated by protein-protein interactions (PPIs). In recent years, affinity purification coupled to mass spectrometry (AP-MS) has been the preferred method to identify cellular PPIs. Here we present a microfluidic-based AP-MS workflow, called on-chip AP-MS, to
    Courtney R Schott et al.
    PloS one, 13(10), e0206427-e0206427 (2018-10-30)
    Dogs diagnosed with appendicular osteosarcoma typically succumb to metastatic disease within a year of diagnosis. The current standard of care for curative intent, amputation followed by adjuvant chemotherapy, increases survival time but chemoresistance is a major contributor to mortality. Unfortunately
    S K Knauer et al.
    Cell death & disease, 1, e51-e51 (2011-03-03)
    Hearing impairment caused by ototoxic insults, such as noise or gentamicin is a worldwide health problem. As the molecular circuitries involved are not yet resolved, current otoprotective therapies are rather empirical than rational. Here, immunohistochemistry and western blotting showed that
    Dong H Hwang et al.
    BMC neuroscience, 10, 117-117 (2009-09-24)
    Contusive spinal cord injury is complicated by a delayed loss of oligodendrocytes, resulting in chronic progressive demyelination. Therefore, transplantation strategies to provide oligodendrocyte lineage cells and to enhance the extent of myelination appear to be justified for spinal cord repair.
    Efraín E Rivera-Serrano et al.
    Journal of molecular and cellular cardiology, 111, 102-113 (2017-08-22)
    Viral myocarditis is a leading cause of sudden death in young adults as the limited turnover of cardiac myocytes renders the heart particularly vulnerable to viral damage. Viruses induce an antiviral type I interferon (IFN-α/β) response in essentially all cell
    View All Related Papers

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