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EHU103811

Sigma-Aldrich

MISSION® esiRNA

targeting human BMPR2

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UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TTTCACTGGATGGTAATGTAACCTTAAAAGCATCATAATAGGTAAAGTCTAATATTAGTTCCCTTAACAAAATCCTAACTGTATACCAGAATTAGGTCACTGAAAGAACTTGATTTGAATTACGTTTAGACAAAAATGATTTAATTGTAAATTCTTAAAACTTTCTAAATGCATAATTGGCAAAAAAAAAAACCCACTGTTACCAGTGTAGGAAGTTACAAGAAGGCACATACTGAATGCTGAAGTATACATATGCTATTTCTCTTAAACCTCAGAGCAACCATATGAGCATTGTAATTAATATTCCCATTTTACAGATGAGGAAACTGAAGCTAAGAGAAGCTAAGTAATATGCCCAAGGTCCACATCTAGTAACAGACAAAGCTGGGATTTCAGTCTATGTCTGCCTCTCTCCACATCTCTTTCATCCATACCACACTGCCTACATGCC

Ensembl | human accession no.

ENSG00000204217

NCBI accession no.

NM_001204

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... BMPR2(659) , BMPR2(659)

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Wenhua Shi et al.
Journal of cellular physiology, 236(6), 4694-4708 (2020-12-08)
The aims of the present study were to examine the molecular mechanisms underlying sphingosine-1-phosphate (S1P)-induced rat pulmonary artery smooth muscle cells (PASMCs) proliferation/migration and to determine the effect of yes-associated protein (YAP) activation on S1P-induced PASMCs proliferation/migration and its potential
Zhixian Yu et al.
PloS one, 11(12), e0168334-e0168334 (2016-12-16)
Approximately 30% of tumor endothelial cells have over-duplicated (>2) centrosomes, which may contribute to abnormal vessel function and drug resistance. Elevated levels of vascular endothelial growth factor A induce excess centrosomes in endothelial cells, but how other features of the
Tomohiko Fukuda et al.
Cell death discovery, 6(1), 139-139 (2020-12-11)
BMP signaling has been found to have tumor-promoting as well as tumor-suppressing effects in different types of tumors. In this study, we investigated the effects of BMP signaling and of BMP inhibitors on ovarian cancer (OC) cells in vitro and
Alex Yuri Simões Sato et al.
Atherosclerosis, 235(1), 45-55 (2014-05-13)
Monocytes and macrophages, together with vascular smooth muscle cells (VSMCs), play key roles at all stages of atherogenesis. There is also growing evidence that BMP signaling is involved in vascular diseases, including atherosclerosis. Here we evaluate the role played by

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