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Merck
CN

E0282

MaxGel ECM

mixture, liquid

Synonym(s):

Human Basement Membrane Extract (BME)

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.71
eCl@ss:
32190102
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Quality Level

form

liquid

storage temp.

−70°C

Application

MaxGel ECM is used for the following applications:
  • Extracellular matrix (ECM) protein binding assays
  • Cell invasion assay
  • Cell culture
This product creates a three-dimensional environment that improves cellular proflieration by promoting cell growth and migration, and has been shown to aid the proliferation of many types of cells, including human embryonic stem cells, neural stem cells, neurons, glia, astrocytes, fibroblasts, hepatocytes, and keratinocytes.

Other Notes

MaxGel ECM contains human extracellular matrix components including collagens, laminin, fibronectin, tenascin, elastin and a number of proteoglycans and glycosaminoglycans. This basement membrane extract reproduces the cooperative interactions between epithelia and mesenchyme that occur during the development and organotypic cell culture of skin.

Legal Information

MaxGel is a trademark of Sigma-Aldrich Co. LLC

Disclaimer

MaxGel will remain stable for at least 1 year when stored at -70°C.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

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Articles

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Human cell derived basement membrane extract (BME) hydrogel for 3D cell culture of primary cell, stem cell and xenograph cancer models.

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Instructions


Bin He et al.
Oncology reports, 29(3), 1115-1123 (2012-12-21)
LIM and SH3 protein 1 (LASP1) is an actin-binding protein which is overexpressed in many types of cancers and plays important roles in cancer progression. however, the role of LASP1 in esophageal squamous cell carcinoma (ESCC) is still unknown. We sought
J Křivánek et al.
Folia biologica, 60 Suppl 1, 30-38 (2014-11-05)
Neural crest cells (NCCs) derive early in vertebrate ontogenesis from neural tube as a population of migratory cells with exquisite differentiation potential. Abnormalities in NCC behaviour are cause of debilitating diseases including cancers and a spectrum of neurocristopathies. Thanks to
Pyrimido[4,5-d]pyrimidin-4(1H)-one derivatives as selective inhibitors of EGFR threonine790 to methionine790 (T790M) mutants.
Tianfeng Xu et al.
Angewandte Chemie (International ed. in English), 52(32), 8387-8390 (2013-06-28)



Global Trade Item Number

SKUGTIN
E0282-1ML04061833601051